Reactome | THEM4,TRIB3 [cytosol]

THEM4,TRIB3 [cytosol]

Stable Identifier

R-HSA-162414

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PKB regulator

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by Insulin receptor (Homo sapiens)
    - Insulin receptor signalling cascade (Homo sapiens)
      - IRS-mediated signalling (Homo sapiens)
        
        PI3K Cascade (Homo sapiens)
        
        Activation of AKT2 (Homo sapiens)
        
        AKT2 binds PIP3 (Homo sapiens)
        
        AKT2:THEM4,TRIB3 [cytosol] (Homo sapiens)
        
        THEM4,TRIB3 [cytosol] (Homo sapiens)
        
        THEM4,TRIB3 [cytosol] (Homo sapiens)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
    - IGF1R signaling cascade (Homo sapiens)
      - IRS-related events triggered by IGF1R (Homo sapiens)
        
        IRS-mediated signalling (Homo sapiens)
        
        PI3K Cascade (Homo sapiens)
        
        Activation of AKT2 (Homo sapiens)
        
        AKT2 binds PIP3 (Homo sapiens)
        
        AKT2:THEM4,TRIB3 [cytosol] (Homo sapiens)
        
        THEM4,TRIB3 [cytosol] (Homo sapiens)
        
        THEM4,TRIB3 [cytosol] (Homo sapiens)

Participants

members

Participates

as an output of

AKT2 binds PIP3 (Homo sapiens)

as a component of

AKT2:THEM4,TRIB3 [cytosol] (Homo sapiens)

Inferred To

trbl [cytosol] (Drosophila melanogaster)

zgc:76966 [cytosol] (Danio rerio)

THEM4,TRIB3 [cytosol] (Bos taurus)

THEM4,TRIB3 [cytosol] (Mus musculus)

THEM4,TRIB3 [cytosol] (Rattus norvegicus)

TRIB3 [cytosol] (Caenorhabditis elegans)

TRIB3 [cytosol] (Sus scrofa)

THEM4 [cytosol] (Dictyostelium discoideum)

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