WDR5 [nucleoplasm]

Stable Identifier
R-HSA-1629838
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, BIG3
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P61964 WDR5
Gene Names
WDR5, BIG3
Chain
initiator methionine:1, chain:2-334
Reference Genes
BioGPS Gene:11091 WDR5
COSMIC (genes):WDR5 WDR5
CTD Gene:11091 WDR5
dbSNP Gene:11091 WDR5
ENSEMBL:ENSG00000196363 WDR5
HGNC:12757 WDR5
KEGG Gene (Homo sapiens):11091 WDR5
Monarch:11091 WDR5
NCBI Gene:11091 WDR5
OMIM:609012 WDR5
UCSC:P61964 WDR5
Reference Transcript
Other Identifiers
0002640131
0002640239
11091
11718374_at
11718375_x_at
11718376_s_at
17090893
223308_s_at
225170_at
2724381
43017_at
43018_g_at
43410_at
43411_g_at
78481_at
8159111
89596_at
A_23_P32558
A_33_P3292417
GE55545
GO:0000123
GO:0001501
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005671
GO:0005975
GO:0006325
GO:0006464
GO:0008150
GO:0008168
GO:0009058
GO:0030154
GO:0031175
GO:0032991
GO:0035064
GO:0035097
GO:0042393
GO:0042800
GO:0043226
GO:0043687
GO:0043966
GO:0043981
GO:0043982
GO:0043984
GO:0044281
GO:0044666
GO:0045652
GO:0045722
GO:0048188
GO:0048856
GO:0051276
GO:0051568
GO:0051571
GO:0051572
GO:0071339
HMNXSV003057386
Hs.13889.0.S1_3p_at
Hs.13889.0.S1_3p_x_at
Hs.323518.0.S1_3p_s_at
ILMN_1728626
ILMN_1737087
PH_hs_0028321
TC09000781.hg
Participates
as a member of
as a component of
as an input of
Inferred To
wdr5 [nucleoplasm] (Danio rerio)
wdr5 [nucleoplasm] (Dictyostelium discoideum)
wdr5 [nucleoplasm] (Xenopus tropicalis)
swd3 [nucleoplasm] (Schizosaccharomyces pombe)
Wdr5 [nucleoplasm] (Mus musculus)
Wdr5 [nucleoplasm] (Rattus norvegicus)
Ghost homologue of WDR5 [nucleoplasm] (Bos taurus)
raf1 [nucleoplasm] (Schizosaccharomyces pombe)
Homologues of WDR5 [nucleoplasm] (Dictyostelium discoideum)
Homologues of WDR5 [nucleoplasm] (Schizosaccharomyces pombe)
WDR5 [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Dictyostelium discoideum)
WDR5 [nucleoplasm] (Sus scrofa)
wds [nucleoplasm] (Drosophila melanogaster)
WDR5B [nucleoplasm] (Gallus gallus)
wdr-5.1 [nucleoplasm] (Caenorhabditis elegans)
Cross References
RefSeq
OpenTargets
HPA
ZINC - Substances
GeneCards
ZINC target
Ensembl
PRO
Orphanet
ZINC - Predictions - Purchasable
PDB
Interactors (85)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q03164 KMT2A  1 0.958 14
 UniProt:Q15291 RBBP5  1 0.948 15
 UniProt:Q9UBL3 ASH2L  1 0.942 15
 UniProt:Q14686 NCOA6  1 0.909 9
 UniProt:Q7Z3B3 KANSL1  1 0.885 12
 UniProt:Q6ZW49 PAXIP1  1 0.864 10
 UniProt:Q9UMN6 KMT2B  1 0.853 7
 UniProt:O14686 KMT2D  1 0.847 9
 UniProt:Q9C005 DPY30  1 0.812 8
 UniProt:Q9NS73 MBIP  1 0.801 6
 UniProt:O15047 SETD1A  1 0.788 5
 UniProt:Q03933 HSF2      0.781 7
 UniProt:P51610 HCFC1  2 0.773 6
 UniProt:Q9P0U4 CXXC1  1 0.758 5
 UniProt:Q2QGD7 ZXDC      0.743 5
 UniProt:P68431 H3C1  59 0.74 11
 UniProt:P54259 ATN1  1 0.738 4
 UniProt:Q9H9L4 KANSL2  1 0.734 4
 IntAct:EBI-15650351 H3TAIL      0.734 5
 UniProt:Q8IWI9 MGA  1 0.725 4
 UniProt:Q99496 RNF2  1 0.725 6
 UniProt:Q9UPS6 SETD1B  1 0.725 4
 UniProt:Q9BTK6 PAGR1  1 0.725 5
 UniProt:Q8NEZ4 KMT2C  1 0.708 5
 UniProt:Q8NFC6 BD1L1      0.708 4
 UniProt:O15550 KDM6A  1 0.708 6
 UniProt:O00255 MEN1  4 0.708 4
 UniProt:Q9H7Z6 KAT8  1 0.69 5
 UniProt:P04637 TP53  27 0.69 5
 UniProt:Q9NS73-5 MBIP      0.666 4
 UniProt:Q6PEV8 F199X      0.666 4
 UniProt:Q96ES7 SGF29  1 0.643 3
 UniProt:Q9ULM3 YEATS2  1 0.643 3
 UniProt:Q9P2R6 RERE      0.643 3
 UniProt:Q9BYE7 PCGF6  1 0.643 4
 UniProt:Q96EZ8 MCRS1  1 0.643 3
 UniProt:O75528 TADA3  1 0.643 3
 UniProt:Q9Y5Z7 HCFC2      0.643 3
 UniProt:Q13547 HDAC1  2 0.643 3
 UniProt:O75461 E2F6  2 0.643 4
 UniProt:Q9BVI0 PHF20  3 0.643 3
 UniProt:Q8IYH5 ZZZ3  1 0.623 3
 UniProt:Q9HCK8 CHD8  1 0.623 3
 UniProt:Q7Z434-1 MAVS      0.591 3
 UniProt:O43823 AKAP8      0.576 3
 UniProt:Q9D1P2  1 0.564 2
 UniProt:O15151 MDM4  5 0.556 3
 UniProt:A7MD48 SRRM4      0.556 3
 UniProt:O76083-2 PDE9A      0.556 3
 UniProt:Q9Y4F3 MARF1      0.556 6
 UniProt:A2RRG2 A2RRG2      0.556 3
 UniProt:Q9Y5X4 NR2E3      0.556 5
 UniProt:Q9H891 Q9H891      0.556 3
 UniProt:Q14204 DYNC1H1  3 0.556 3
 UniProt:Q9Y2D8 ADIP      0.556 3
 UniProt:Q9UJX6 ANAPC2  2 0.556 3
 UniProt:P10074 TZAP      0.556 3
 UniProt:Q6FHY5 Q6FHY5      0.556 3
 UniProt:Q86V38 Q86V38      0.556 3
 UniProt:Q96PG8 BBC3B      0.556 3
 UniProt:Q92876 KLK6      0.556 3
 UniProt:Q92794 KAT6A  3 0.556 4
 UniProt:O00308 WWP2  1 0.556 3
 IntAct:EBI-15662162 H3-8      0.544 2
 UniProt:P58004 SESN2  1 0.527 2
 UniProt:Q92769 HDAC2  2 0.527 2
 UniProt:Q6UXN9 WDR82      0.527 2
 UniProt:P61513 RPL37A  1 0.527 2
 UniProt:O15294 OGT  2 0.527 3
 UniProt:Q9P2N6 KANSL3  1 0.527 2
 UniProt:Q06587 RING1  1 0.527 3
 UniProt:Q6ZSY5 PPR3F      0.527 2
 UniProt:P19784 CSNK2A2  2 0.527 2
 UniProt:Q9H8E8 KAT14  1 0.527 2
 UniProt:Q8N488 RYBP  1 0.527 2
 UniProt:P83916 CBX1  1 0.527 2
 UniProt:Q13185 CBX3  1 0.527 3
 UniProt:Q6NZQ4 Paxip1  2 0.527 3
 UniProt:Q969R5 L3MBTL2  2 0.527 3
 UniProt:Q14186 TFDP1  1 0.527 3
 UniProt:Q13114 TRAF3  5 0.524 2
 UniProt:Q9Y4K3 TRAF6  8 0.524 2
 UniProt:Q9NYB0 TERF2IP  1 0.508 2
 UniProt:Q9WTL8 Arntl  2 0.508 2
 UniProt:Q9H4Z2 ZNF335  1 0.462 2
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