Reactome: A Curated Pathway Database

WDR5

Stable Identifier
R-HSA-1629838
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, BIG3
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
WDR5, BIG3
Chain
initiator methionine:1, chain:2-334
Reference Genes
Reference Transcript
Other Identifiers
 0002640131  0002640239  11091  11718374_at  11718375_x_at
 11718376_s_at  17090893  223308_s_at  225170_at  2724381
 2CNX  2CO0  2G99  2G9A  2GNQ
 2H13  2H14  2H68  2H6K  2H6N
 2H6Q  2H9L  2H9M  2H9N  2H9P
 2O9K  3EG6  3EMH  3MXX  3N0D
 3N0E  3P4F  3PSL  3SMR  3UR4
 3UVK  3UVL  3UVM  3UVN  3UVO
 43017_at  43018_g_at  43410_at  43411_g_at  47182
 4A7J  4CY1  4CY2  4ERQ  4ERY
 4ERZ  4ES0  4ESG  4EWR  4GM3
 4GM8  4GM9  4GMB  4IA9  4O45
 4QL1  4Y7R  5EAL  5EAM  5EAP
 5EAR  5SXM  78481_at  8159111  89596_at
 A_23_P32558  A_33_P3292417  AAH01635  AJ011376  AK000552
 BAA91248  BC001635  CAB66159  CCDS6981  ENSG00000196363
 ENSP00000351446  ENST00000358625  EntrezGene:11091  GE55545  GO:0000123
 GO:0001501  GO:0003674  GO:0005515  GO:0005575  GO:0005622
 GO:0005623  GO:0005634  GO:0005654  GO:0005671  GO:0005815
 GO:0005856  GO:0005929  GO:0005975  GO:0006351  GO:0006355
 GO:0006464  GO:0008150  GO:0008168  GO:0009058  GO:0016569
 GO:0016746  GO:0018024  GO:0022607  GO:0030154  GO:0031175
 GO:0034641  GO:0035064  GO:0035097  GO:0035948  GO:0036064
 GO:0042393  GO:0042800  GO:0043226  GO:0043234  GO:0043687
 GO:0043966  GO:0043981  GO:0043982  GO:0043984  GO:0043995
 GO:0043996  GO:0044281  GO:0044666  GO:0046972  GO:0048188
 GO:0048856  GO:0051276  GO:0051568  GO:0060271  GO:0071339
 HGNC:12757  HPA047182  Hs.13889.0.S1_3p_at  Hs.13889.0.S1_3p_x_at  Hs.323518.0.S1_3p_s_at
 Hs.397638  ILMN_1728626  ILMN_1737087  IPR001680  IPR015943
 IPR017986  IPR019775  IPR020472  MIM:609012  NM_017588
 NM_052821  NP_060058  NP_438172  PF00400  PH_hs_0028321
 PR00320  SM00320  TC09000781.hg  uc004cey.4  UPI00000040F5
 WDR5  WDR5-201  XM_005272163  XP_005272220
Participant Of
Inferred To
Cross References
UCSC human
GeneCards
ZINC - Substances
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.922 Q15291 RBBP5_HUMAN 12
0.922 Q9UBL3 ASH2L_HUMAN 12
0.9 Q03164 KMT2A_HUMAN 11
0.804 Q7Z3B3 KANL1_HUMAN 10
0.802 Q14686 NCOA6_HUMAN 5
0.773 Q6ZW49 PAXI1_HUMAN 8
0.773 O14686 KMT2D_HUMAN 7
0.74 P68431 H31_HUMAN 11
0.712 Q9NS73 MBIP1_HUMAN 4
0.708 P51610 HCFC1_HUMAN 5
0.696 Q03933 HSF2_HUMAN 5
0.69 Q9P0U4 CXXC1_HUMAN 4
0.656 Q9H9L4 KANL2_HUMAN 3
0.656 Q9UMN6 KMT2B_HUMAN 3
0.643 Q9BTK6 PAGR1_HUMAN 4
0.643 O15047 SET1A_HUMAN 3
0.623 Q9HCK8 CHD8_HUMAN 3
0.623 Q8NEZ4 KMT2C_HUMAN 4
0.621 Q2QGD7 ZXDC_HUMAN 3
0.621 Q6PEV8 F199X_HUMAN 3
0.597 Q9H7Z6 KAT8_HUMAN 4
0.597 P04637 P53_HUMAN 3
0.564 Q9D1P2 KAT8_MOUSE 2
0.556 Q9H891 Q9H891_HUMAN 3
0.556 Q92794 KAT6A_HUMAN 4
0.556 A2RRG2 A2RRG2_HUMAN 3
0.556 Q9Y2D8 ADIP_HUMAN 3
0.556 Q9NS73-5 MBIP 3
0.547 P54259 ATN1_HUMAN 2
0.527 Q99496 RING2_HUMAN 4
0.527 O00255 MEN1_HUMAN 2
0.527 O15550 KDM6A_HUMAN 4
0.527 Q13547 HDAC1_HUMAN 2
0.527 Q9C005 DPY30_HUMAN 2
0.527 Q6UXN9 WDR82_HUMAN 2
0.527 Q96EZ8 MCRS1_HUMAN 2
0.527 Q8IWI9 MGAP_HUMAN 2
0.527 P19784 CSK22_HUMAN 2
0.527 Q9UPS6 SET1B_HUMAN 2
0.527 O15294 OGT1_HUMAN 3
0.527 Q9BVI0 PHF20_HUMAN 2
0.527 Q6NZQ4 PAXI1_MOUSE 3
0.508 Q9NYB0 TE2IP_HUMAN 2
0.508 Q9WTL8 BMAL1_MOUSE 2
0.488 Q9Y4F3 MARF1_HUMAN 4
0.488 P10074 ZBT48_HUMAN 2
0.488 A7MD48 SRRM4_HUMAN 2
0.488 Q9Y5X4 NR2E3_HUMAN 2
0.488 A4D127 A4D127_HUMAN 2
0.488 O15151 MDM4_HUMAN 2
0.488 Q9UJX6 ANC2_HUMAN 2
0.488 O76083-2 PDE9A 2
0.488 O00308 WWP2_HUMAN 2