Reactome | ABHD5 [lipid droplet]

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ABHD5 [lipid droplet]

Stable Identifier

R-HSA-163485

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lipid droplet

Synonyms

CGI-58, abhydrolase domain containing 5

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8WTS1 ABHD5

Gene Names

ABHD5, NCIE2, CGI-58

Chain

initiator methionine:1, chain:2-349

Reference Genes

BioGPS Gene:51099 ABHD5

COSMIC (genes):ABHD5 ABHD5

CTD Gene:51099 ABHD5

dbSNP Gene:51099 ABHD5

ENSEMBL:ENSG00000011198 ABHD5

HGNC:21396 ABHD5

KEGG:hsa:51099 ABHD5

Monarch:51099 ABHD5

NCBI Gene:51099 ABHD5

OMIM:604780 ABHD5

UCSC:Q8WTS1 ABHD5

Reference Transcript

Other Identifiers

11723701_at

11723702_at

11723703_s_at

11723704_at

11723705_at

11723706_at

16939815

213805_PM_at

213805_at

213935_PM_at

213935_at

218739_PM_at

218739_at

2619763

2619764

2619765

2619766

2619768

2619769

2619771

2619772

2619773

2619776

2619778

2619779

2619780

2619781

2619782

2619783

2619784

2619785

2619786

2619787

2619788

2619789

2619790

2619793

33309_at

33310_at

44987_at

50722_at

51099

56232_at

80687_at

8079153

A_14_P104748

A_23_P250294

GE58646

GO:0003841

GO:0005515

GO:0005654

GO:0005737

GO:0005811

GO:0005829

GO:0006508

GO:0006629

GO:0006631

GO:0006654

GO:0008233

GO:0008654

GO:0010891

GO:0010898

GO:0016740

GO:0016746

GO:0016787

GO:0030154

GO:0042171

GO:0043226

GO:0050996

GO:0052689

GO:0055088

GO:0060229

GO:0098772

HMNXSV003020842

Hs.184019.0.S1_3p_at

Hs.184019.1.S1_3p_at

ILMN_1655702

PH_hs_0001705

TC03000231.hg

g7705770_3p_at

Participates

as a component of

perilipin:ABHD5 complex [lipid droplet] (Homo sapiens)

Other forms of this molecule

ABHD5 [cytosol]

Cross References

RefSeq

XP_047304199.1, NP_057090.2, XP_054202694.1, NP_001342115.1

OpenTargets

ENSG00000011198

ENSEMBL

ENST00000644371, ENST00000649763, ENSP00000497701, ENSP00000495778, ENSG00000011198

IntEnz

2.3.1.51

HPA

ENSG00000011198-ABHD5

GeneCards

ABHD5

PRO

Q8WTS1

Pharos - Targets

Q8WTS1

GlyGen

Q8WTS1

Orphanet

ABHD5

HMDB Protein

HMDBP11598

Interactors (27)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:O60664 PLIN3	7	p-PLIN3 [lysosomal lumen] (R-HSA-9639396) p-PLIN3 [cytosol] (R-HSA-9613664) p-PLIN3 [lipid droplet] (R-HSA-9613539) PLIN3 [lipid droplet] (R-HSA-9613337) p-PLIN3 [late endosome lumen] (R-HSA-9639393) PLIN3 [cytosol] (R-HSA-6814628) PLIN3 [transport vesicle] (R-HSA-6813900)	0.556	3
UniProt:Q05329 GAD2	2	PXLP-K396-GAD2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888582) PXLP-K396-GAD2 [plasma membrane] (R-HSA-936509)	0.556	3
UniProt:Q99541 PLIN2	6	PLIN2 [plasma membrane] (R-HSA-400160) p-PLIN2 [late endosome lumen] (R-HSA-9639398) PLIN2 [lipid droplet] (R-HSA-9613345) p-PLIN2 [lipid droplet] (R-HSA-9613544) p-PLIN2 [cytosol] (R-HSA-9613667) p-PLIN2 [lysosomal lumen] (R-HSA-9639397)	0.556	3
UniProt:Q8N4M1-3 SLC44A3			0.556	3
UniProt:P48058-2 P480582			0.556	3
UniProt:Q8NI60 COQ8A	1	COQ8A [mitochondrial inner membrane] (R-HSA-9856284)	0.556	3
UniProt:Q5T4B2 GT253			0.556	3
UniProt:P51793 CLCN4	1	CLCN4 [endosome membrane] (R-HSA-2671932)	0.556	3
UniProt:A6NKB5-5 A6NKB55			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q6PEW1 ZCH12			0.556	3
UniProt:Q00G26 PLIN5			0.556	3
UniProt:O43399 TPD54			0.556	3
UniProt:Q9BVN2 RUSC1			0.556	3
UniProt:Q9Y225-2 RNF24			0.556	3
UniProt:O00258 GET1	1	WRB [endoplasmic reticulum membrane] (R-HSA-9609521)	0.556	3
UniProt:Q9NQG6 MIEF1	1	MIEF1 [mitochondrial matrix] (R-HSA-9937401)	0.556	5
IntAct:EBI-22326698 CCSB ORF ID			0.556	3
UniProt:Q9Y371 SHLB1			0.556	3
UniProt:Q8N0V3 RBFA			0.556	3
UniProt:O75563 SKAP2	1	SKAP2 [cytosol] (R-HSA-390927)	0.527	2
UniProt:Q9NVV0 TM38B			0.527	2
UniProt:P01111 NRAS	20	S-Farn-Me PalmS NRAS [plasma membrane] (R-HSA-9647910) proNRAS [cytosol] (R-HSA-9647758) S-Farn-proNRAS [endoplasmic reticulum membrane] (R-HSA-9647928) S-Farn NRAS [endoplasmic reticulum membrane] (R-HSA-9647782) S-Farn-Me NRAS [endoplasmic reticulum membrane] (R-HSA-9647891) S-Farn-Me PalmS NRAS [Golgi membrane] (R-HSA-9647906) NRAS [plasma membrane] (R-HSA-62725) S-Farn-Me NRAS [plasma membrane] (R-HSA-9647893) NRAS Q60E [plasma membrane] (R-HSA-9656589) NRAS G12D [plasma membrane] (R-HSA-6802339) NRAS G12S [plasma membrane] (R-HSA-6802347) NRAS G13D [plasma membrane] (R-HSA-6802363) NRAS Q61K [plasma membrane] (R-HSA-6802446) NRAS Q61L [plasma membrane] (R-HSA-6802455) NRAS Q61R [plasma membrane] (R-HSA-6802461) NRAS Q61P [plasma membrane] (R-HSA-9649680) NRAS G12A [plasma membrane] (R-HSA-9649657) NRAS G12R [plasma membrane] (R-HSA-9649662) NRAS G12C [plasma membrane] (R-HSA-9649660) NRAS G12V [plasma membrane] (R-HSA-9649666)	0.527	2
UniProt:Q96BY9 SARAF			0.527	2
UniProt:Q8IWR1 TRI59			0.527	2
UniProt:O75312 ZPR1			0.527	2

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