PPP1CA [cytosol]

Stable Identifier
R-HSA-163525
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
PP1CA, Serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit , PP-1A
Locations in the PathwayBrowser for interactor UniProt:Q9H4A3 WNK1
Expand all
External Reference Information
External Reference
UniProt:P62136 PPP1CA
Gene Names
PPP1CA, PPP1A
Chain
initiator methionine:1, chain:2-330
Reference Genes
BioGPS Gene:5499 PPP1CA
COSMIC (genes):PPP1CA PPP1CA
CTD Gene:5499 PPP1CA
dbSNP Gene:5499 PPP1CA
ENSEMBL:ENSG00000172531 PPP1CA
HGNC:9281 PPP1CA
KEGG Gene (Homo sapiens):5499 PPP1CA
Monarch:5499 PPP1CA
NCBI Gene:5499 PPP1CA
OMIM:176875 PPP1CA
UCSC:P62136 PPP1CA
Reference Transcript
Other Identifiers
0006290129
11737907_s_at
11754633_x_at
16740977
200846_s_at
32157_at
3378791
3378792
3378794
3378795
3378797
3378799
3378800
3378801
3378802
3378804
3378805
5499
74577_s_at
7949765
954_s_at
A_23_P323227
A_23_P434710
GE79535
GO:0000164
GO:0000228
GO:0000784
GO:0003674
GO:0004721
GO:0004722
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005829
GO:0005886
GO:0005912
GO:0005975
GO:0005977
GO:0005979
GO:0005981
GO:0006091
GO:0006412
GO:0006464
GO:0006470
GO:0006950
GO:0007049
GO:0007155
GO:0007165
GO:0007267
GO:0008150
GO:0008157
GO:0008219
GO:0009056
GO:0009058
GO:0010288
GO:0016032
GO:0016311
GO:0016787
GO:0016791
GO:0019899
GO:0030324
GO:0032091
GO:0032922
GO:0032991
GO:0034641
GO:0035970
GO:0036496
GO:0042587
GO:0042752
GO:0043005
GO:0043021
GO:0043025
GO:0043153
GO:0043167
GO:0043197
GO:0043204
GO:0043226
GO:0044281
GO:0044403
GO:0044877
GO:0046872
GO:0048754
GO:0048856
GO:0051301
GO:0060828
GO:0070062
GO:0070262
GO:0072357
GO:0098609
GO:0098641
GO:0098793
GO:1904886
GO:2001241
ILMN_1695827
ILMN_2377980
PH_hs_0010846
TC11001981.hg
g4506002_3p_a_at
Participant Of
input
hasComponent
hasMember
Inferred To
ppp1cc [cytosol] (Danio rerio)
Ppp1ca [cytosol] (Mus musculus)
Ppp1ca [cytosol] (Rattus norvegicus)
Cross References
RefSeq
Target Pathogen
OpenTargets
GeneCards
HPA
ZINC target
Ensembl
PRO
HMDB Protein
PDB
Interactors (119)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P41236 IPP2      0.949 12
 UniProt:Q96KQ4 PPP1R13B  1 0.932 11
 UniProt:Q12972 PP1R8      0.904 8
 UniProt:Q8WUF5 PPP1R13L  1 0.892 9
 UniProt:Q9H175 CSRN2      0.885 10
 UniProt:Q13625 TP53BP2  1 0.86 9
 UniProt:Q96SB3 NEB2      0.857 6
 UniProt:Q15435 PP1R7      0.84 8
 UniProt:Q96S65 CSRN1      0.831 8
 UniProt:P36873 PPP1CC  1 0.814 7
 UniProt:O35274 NEB2      0.813 8
 UniProt:Q9Y2W2 WBP11  1 0.796 5
 UniProt:O75864 PPR37      0.789 5
 UniProt:Q5SWA1 PR15B      0.778 5
 UniProt:P06400 RB1  394 0.771 5
 UniProt:Q6NYC8 PPR18      0.768 5
 UniProt:Q5UIP0 RIF1  1 0.765 5
 UniProt:Q9NWS0 PIHD1      0.76 5
 UniProt:P13807 GYS1  3 0.76 5
 UniProt:Q9NUG6 PDRG1      0.76 5
 UniProt:O60927 PP1RB      0.76 5
 UniProt:Q9UBK9 UXT  1 0.76 5
 UniProt:Q96MX6 WDR92      0.76 5
 UniProt:P19388 POLR2E  2 0.76 5
 UniProt:Q9UQK1 PPP1R3C  2 0.743 5
 UniProt:Q6PJW8 CNST      0.737 4
 UniProt:Q7Z699 SPRED1  2 0.737 4
 UniProt:Q8NI77 KIF18A  1 0.73 4
 UniProt:Q86WC6 PPR27      0.715 5
 UniProt:Q96QC0 PP1RA      0.702 4
 UniProt:Q12972-1 PPP1R8      0.693 6
 UniProt:Q9H6T3 RPAP3      0.69 4
 UniProt:O94763 RMP      0.69 4
 UniProt:Q14684 RRP1B      0.667 3
 UniProt:Q6ZMQ8 LMTK1      0.667 3
 UniProt:Q96T49 PP16B      0.666 4
 UniProt:Q86XI6 PPR3B      0.666 4
 UniProt:Q4KMQ1-2 TPRN      0.666 6
 UniProt:P42858 HTT  1 0.666 10
 UniProt:Q12972-2 PPP1R8      0.666 7
 UniProt:O95685 PPR3D      0.659 3
 UniProt:Q8TEC5 SH3R2      0.658 3
 UniProt:Q7Z5V6 PPR32      0.658 3
 UniProt:Q9H788 SH24A      0.656 3
 UniProt:Q5S007 LRRK2  1 0.65 6
 UniProt:P46937 YAP1  7 0.643 3
 UniProt:P62140 PPP1CB  4 0.638 3
 UniProt:Q9GZN8 CT027      0.638 3
 UniProt:O35867 NEB1      0.618 3
 UniProt:P49750 YLPM1      0.613 3
 UniProt:O75807 PPP1R15A  1 0.613 5
 UniProt:Q4KMQ1 TPRN      0.613 3
 UniProt:Q8NHQ8 RASF8      0.597 3
 UniProt:Q15834 CC85B      0.597 3
 UniProt:Q9Y265 RUVBL1  1 0.597 3
 UniProt:Q9H792 PEAK1      0.597 3
 UniProt:Q6UXN9 WDR82      0.597 3
 UniProt:O94842 TOX4      0.597 3
 UniProt:O14802 POLR3A  2 0.597 3
 UniProt:Q02833 RASF7      0.597 3
 UniProt:A6NKD9 CC85C      0.597 3
 UniProt:Q5T8A7 PPR26      0.592 2
 UniProt:O00566 MPHOSPH10  1 0.592 2
 UniProt:Q8NG31 KNL1  2 0.592 2
 UniProt:Q9HCH5 SYTL2      0.592 2
 UniProt:O95400 CD2BP2  1 0.592 2
 UniProt:Q99459 CDC5L  1 0.59 2
 UniProt:Q5JTV8 TOIP1      0.573 2
 UniProt:P31749 AKT1  13 0.571 4
 UniProt:Q80W00 PP1RA      0.564 2
 UniProt:Q05BL1 Q05BL1      0.556 3
 UniProt:P43405-2 P434052      0.556 3
 UniProt:Q6NXS1 IPP2B      0.556 3
 UniProt:O14990 IPP2C      0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:P04271 S100B  1 0.556 3
 UniProt:O95793 STAU1      0.553 2
 UniProt:Q96S59 RANBP9  1 0.553 2
 UniProt:O95405 ZFYVE9      0.553 3
 UniProt:Q96KR7 PHAR3      0.547 2
 UniProt:Q7Z3T8 ZFYVE16  1 0.547 2
 UniProt:Q9H7J1 PPR3E      0.547 2
 UniProt:Q9UPR0 PLCL2      0.547 2
 UniProt:Q8TEP8 CEP192  1 0.544 2
 UniProt:Q14C87 T132D      0.544 2
 UniProt:Q9NX63 CHCHD3  3 0.544 2
 UniProt:Q9H4A3 WNK1  1 0.544 2
 UniProt:Q9HBF4 ZFYV1      0.544 2
 UniProt:Q92796 DLG3  2 0.544 2
 UniProt:Q8TEL6 TRPC4AP  1 0.544 2
 UniProt:A8K8P3 SFI1  1 0.544 2
 UniProt:P55199 ELL  1 0.544 2
 UniProt:P49815 TSC2  4 0.544 2
 UniProt:P16989 YBOX3      0.537 3
 UniProt:P49790 NUP153  1 0.527 2
 UniProt:P09622 DLD  1 0.527 2
 UniProt:Q9ULJ8 NEB1      0.527 2
 UniProt:P60484 PTEN  122 0.524 2
 UniProt:P38398 BRCA1  27 0.524 2
 UniProt:O14727 APAF1  4 0.524 2
 UniProt:P63208 SKP1  2 0.524 3
 UniProt:O15169 AXIN1  11 0.524 4
 UniProt:P12830 CDH1  10 0.524 2
 UniProt:P61962 DCAF7  2 0.508 2
 UniProt:Q15691 MAPRE1  1 0.508 2
 UniProt:O08785 Clock  2 0.508 2
 UniProt:O60828 PQBP1  1 0.508 2
 UniProt:P36313 ICP34      0.508 4
 UniProt:Q76TK5 Q76TK5      0.499 2
 UniProt:P55072 VCP  8 0.499 2
 UniProt:Q9NVI7 ATD3A      0.462 2
 UniProt:Q9UHV9 PFDN2  1 0.462 2
 UniProt:P40227 CCT6A  1 0.462 2
 UniProt:Q96RT1 ERBIN  1 0.462 2
 UniProt:O15212 PFDN6  1 0.462 2
 UniProt:Q8TEW0 PARD3  3 0.462 2
 UniProt:Q8IWX8 CHERP  1 0.462 2
 UniProt:Q562F6 SGO2  1 0.462 4
 UniProt:Q9Y230 RUVBL2  1 0.462 2
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