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UQCRH [mitochondrial inner membrane]
Stable Identifier
R-HSA-164286
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Ubiquinol-cytochrome c reductase complex 11 kDa protein, Complex III subunit VIII
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex III assembly (Homo sapiens)
Intermediate II binds CYC1, UQCRC1, UQCRC2, UQCRH (Homo sapiens)
Late core complex monomer [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Late core complex dimer binds UQCR10. UQCR11, UQCRFS1 (Homo sapiens)
Dimer of Late core complex:UQCR10:UQCR11:holo-UQCRFS1(1-274) [mitochondrial inner membrane] (Homo sapiens)
Late core complex:UQCR10:UQCR11:holo-UQCRFS1(1-274) [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Late core complex dimer [mitochondrial inner membrane] (Homo sapiens)
Late core complex monomer [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Late core complex dimerizes (Homo sapiens)
Late core complex dimer [mitochondrial inner membrane] (Homo sapiens)
Late core complex monomer [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Late core complex monomer [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
TTC19 clears UQCRFS1 fragments from Complex III (Homo sapiens)
Cytochrome c reductase [mitochondrial inner membrane] (Homo sapiens)
Complex III monomer [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Dimer of Late core complex:UQCR10:UQCR11:holo-UQCRFS1(79-274):Fragments [mitochondrial inner membrane] (Homo sapiens)
Late core complex:UQCR10:UQCR11:holo-UQCRFS1(79-274):Fragments [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Unknown peptidase cleaves UQCRFS1 subunit (Homo sapiens)
Dimer of Late core complex:UQCR10:UQCR11:holo-UQCRFS1(1-274) [mitochondrial inner membrane] (Homo sapiens)
Late core complex:UQCR10:UQCR11:holo-UQCRFS1(1-274) [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Dimer of Late core complex:UQCR10:UQCR11:holo-UQCRFS1(79-274):Fragments [mitochondrial inner membrane] (Homo sapiens)
Late core complex:UQCR10:UQCR11:holo-UQCRFS1(79-274):Fragments [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
Electron transfer from ubiquinol to cytochrome c of complex III (Homo sapiens)
Cytochrome c reductase [mitochondrial inner membrane] (Homo sapiens)
Complex III monomer [mitochondrial inner membrane] (Homo sapiens)
UQCRH [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P07919 UQCRH
Gene Names
UQCRH
Chain
transit peptide:1-13, chain:14-91
Reference Genes
BioGPS Gene:7388 UQCRH
COSMIC (genes):UQCRH UQCRH
CTD Gene:7388 UQCRH
dbSNP Gene:7388 UQCRH
ENSEMBL:ENSG00000173660 UQCRH
ENSEMBL_homo_sapiens_GENE:ENSG00000173660.12 UQCRH
HGNC:12590 UQCRH
KEGG Gene (Homo sapiens):7388 UQCRH
Monarch:7388 UQCRH
NCBI Gene:7388 UQCRH
OMIM:613844 UQCRH
UCSC:P07919 UQCRH
Reference Transcript
RefSeq:NM_006004.3 UQCRH
Other Identifiers
11744455_s_at
202233_PM_s_at
202233_s_at
2334690
2334691
2334699
2334704
2334705
2397796
2397797
2397798
36104_at
7388
74613_s_at
7901212
7912670
A_33_P3299892
GE60235
GO:0003824
GO:0005215
GO:0005515
GO:0005739
GO:0005743
GO:0005746
GO:0005750
GO:0006091
GO:0006119
GO:0006122
GO:0008121
GO:0009060
GO:0016020
GO:0016491
GO:0043226
GO:0045333
GO:0055085
GO:0070469
GO:1902600
HMNXSV003052909
ILMN_2232936
TC01000583.hg
Y00764_at
g5174744_3p_a_at
Participates
as an input of
Intermediate II binds CYC1, UQCRC1, UQCRC2, UQCRH (Homo sapiens)
as a component of
Late core complex monomer [mitochondrial inner membrane] (Homo sapiens)
Late core complex:UQCR10:UQCR11:holo-UQCRFS1(1-274) [mitochondrial inner membrane] (Homo sapiens)
Late core complex:UQCR10:UQCR11:holo-UQCRFS1(79-274):Fragments [mitochondrial inner membrane] (Homo sapiens)
Complex III monomer [mitochondrial inner membrane] (Homo sapiens)
Inferred To
uqcrh [mitochondrial inner membrane]
(Danio rerio)
uqcrh [mitochondrial inner membrane]
(Dictyostelium discoideum)
QCR6 [mitochondrial inner membrane]
(Saccharomyces cerevisiae)
UQCR-11 [mitochondrial inner membrane]
(Drosophila melanogaster)
UQCRH [mitochondrial inner membrane]
(Bos taurus)
UQCRH [mitochondrial inner membrane]
(Caenorhabditis elegans)
UQCRH [mitochondrial inner membrane]
(Gallus gallus)
UQCRH [mitochondrial inner membrane]
(Sus scrofa)
Uqcrh [mitochondrial inner membrane]
(Mus musculus)
Uqcrh [mitochondrial inner membrane]
(Rattus norvegicus)
qcr6 [mitochondrial inner membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_005995.2
OpenTargets
ENSG00000173660
GeneCards
P07919
HPA
ENSG00000173660-UQCRH
Ensembl
ENSG00000173660
,
ENST00000311672
,
ENSP00000309565
PRO
P07919
Pharos - Targets
P07919
HMDB Protein
HMDBP00992
PDB
5XTE
,
5XTI
,
5XTH
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96BM9 ARL8A
3
ARL8A [ficolin-1-rich granule membrane]
(R-HSA-6801066)
ARL8A [plasma membrane]
(R-HSA-6801539)
ARL8A [azurophil granule membrane]
(R-HSA-6801069)
0.718
6
UniProt:Q9BT67 NFIP1
0.556
3
UniProt:Q9NV92 NFIP2
0.556
3
UniProt:O14668 TMG1
0.556
3
UniProt:Q96H71 Q96H71
0.556
3
UniProt:Q9Y225 RNF24
0.556
3
UniProt:O00399 DCTN6
1
DCTN6 [cytosol]
(R-HSA-2029035)
0.527
2
UniProt:P42025 ACTR1B
4
ACTR1B [cytosol]
(R-HSA-2228745)
ACTR1B [secretory granule lumen]
(R-HSA-6801082)
ACTR1B [extracellular region]
(R-HSA-6806503)
ACTR1B [ficolin-1-rich granule lumen]
(R-HSA-6801063)
0.527
2
UniProt:P08574 CYC1
3
CYC1(1-325) [mitochondrial intermembrane space]
(R-HSA-1267962)
CYC1(1-325) [cytosol]
(R-HSA-1267995)
CYC1 [mitochondrial inner membrane]
(R-HSA-164277)
0.527
2
UniProt:Q5JSL3 DOCK11
1
DOCK11 [cytosol]
(R-HSA-1012996)
0.527
2
UniProt:Q9NZ32 ACTR10
4
ACTR10 [cytosol]
(R-HSA-6801556)
ACTR10 [ficolin-1-rich granule lumen]
(R-HSA-6801072)
ACTR10 [extracellular region]
(R-HSA-6806245)
ACTR10 [azurophil granule lumen]
(R-HSA-6801080)
0.527
2
UniProt:P00156 MT-CYB
1
MT-CYB [mitochondrial inner membrane]
(R-HSA-164281)
0.527
2
UniProt:P22695 UQCRC2
1
UQCRC2 [mitochondrial inner membrane]
(R-HSA-164280)
0.527
2
UniProt:O14548 COX7A2L
1
COX7A2L [mitochondrial inner membrane]
(R-HSA-164310)
0.527
2
UniProt:Q9BTE1 DCTN5
1
DCTN5 [cytosol]
(R-HSA-2029012)
0.527
2
UniProt:O14949 UQCRQ
1
UQCRQ [mitochondrial inner membrane]
(R-HSA-164283)
0.527
2
UniProt:P14927 UQCRB
1
UQCRB [mitochondrial inner membrane]
(R-HSA-164287)
0.527
3
UniProt:P07437 TUBB
3
TUBB [cytosol]
(R-HSA-9020816)
TUBB [azurophil granule lumen]
(R-HSA-6799370)
TUBB [extracellular region]
(R-HSA-380317)
0.527
2
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.527
4
UniProt:P31930 UQCRC1
1
UQCRC1 [mitochondrial inner membrane]
(R-HSA-164284)
0.527
2
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