Reactome | ATP5F1 [mitochondrial inner membrane]

ATP5F1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-164537

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase B chain

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5F1 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5F1 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P24539 ATP5PB

Gene Names

ATP5PB, ATP5F1

Chain

transit peptide:1-42, chain:43-256

Reference Genes

BioGPS Gene:515 ATP5PB

COSMIC (genes):ATP5PB ATP5PB

CTD Gene:515 ATP5PB

dbSNP Gene:515 ATP5PB

ENSEMBL:ENSG00000116459 ATP5F1

HGNC:840 ATP5PB

KEGG Gene (Homo sapiens):515 ATP5PB

Monarch:515 ATP5PB

NCBI Gene:515 ATP5PB

OMIM:603270 ATP5PB

Reference Transcript

RefSeq:NM_001688.4 ATP5PB

Other Identifiers

0005720368

11734652_s_at

11734653_x_at

11734654_at

11734655_x_at

16668689

211755_s_at

2351821

2351822

2351830

2351832

2351833

2351835

2351837

2351838

2351839

2351840

2351841

2351843

2351845

243501_at

3792570

3812170

41228_r_at

515

68528_r_at

7903972

A_23_P46275

A_24_P659099

D28383_at

GE59857

GO:0000276

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005743

GO:0005753

GO:0005759

GO:0006091

GO:0006754

GO:0006810

GO:0006811

GO:0007005

GO:0008150

GO:0009058

GO:0015078

GO:0015986

GO:0016020

GO:0016874

GO:0021762

GO:0022857

GO:0032991

GO:0034641

GO:0042407

GO:0042776

GO:0043226

GO:0044281

GO:0045263

GO:0046933

GO:0048856

GO:0055085

GO:0061024

HMNXSV003050712

Hs.191834.0.A1_3p_at

ILMN_1672191

ILMN_1721989

ILMN_1899664

PH_hs_0004670

TC01000977.hg

X60221_at

g13543617_3p_s_at

Participates

as a component of

ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ATP4 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

ATP5PB [mitochondrial inner membrane] (Canis familiaris)

ATP5PB [mitochondrial inner membrane] (Gallus gallus)

ATP5PB [mitochondrial inner membrane] (Sus scrofa)

Atp5pb [mitochondrial inner membrane] (Mus musculus)

Atp5pb [mitochondrial inner membrane] (Rattus norvegicus)

ATPsynB [mitochondrial inner membrane] (Drosophila melanogaster)

atp4 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

asb-2 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATP5F1 [mitochondrial inner membrane] (Bos taurus)

atp5pb [mitochondrial inner membrane] (Danio rerio)

Cross References

RefSeq

NP_001679.2

Target Pathogen

5b354852be737e166372ec90

OpenTargets

ENSG00000116459

GeneCards

P24539

HPA

ENSG00000116459-ATP5PB

Ensembl

ENSP00000358737, ENST00000369722, ENSG00000116459

PRO

P24539

HMDB Protein

HMDBP01419

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06576 ATP5F1B	6	ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B [mitochondrial inner membrane] (R-HSA-1299441) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B [mitochondrial matrix] (R-HSA-164576)	0.564	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P10809 HSPD1	6	HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1 [mitochondrial matrix] (R-HSA-1299448) HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963)	0.483	2
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2