Release of the HIV mRNA and Crm1 from Rev in the cytoplasm

Stable Identifier
R-HSA-165028
Type
Reaction
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
Locations in the PathwayBrowser
Summation

The association of RanBp1 with RanGTP:CRM1:Rev promotes disassembly of the complex and release of the Rev:RNA cargo (Mahboobi et al. 2015).

Literature References
PubMed ID Title Journal Year
25723178 The interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cycle

Mahboobi, SH, Javanpour, AA, Mofrad, MR

PLoS ONE 2015
Participants
Participant Of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 HIV infection
Authored
Reviewed