Hydrolysis of Ran:GTP to Ran:GDP

Stable Identifier
R-HSA-165055
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
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Ran-GAP, a Ran-specific GTPase-activating protein converts Ran-GTP to Ran-GDP, producing a Ran-GTP gradient across the nuclear membrane.

Literature References
PubMed ID Title Journal Year
7878053 Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport

Bischoff, FR, Krebber, H, Kempf, T, Hermes, I, Ponstingl, H

Proc Natl Acad Sci U S A 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
GTPase activity of Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [cytosol]
Physical Entity
Activity
This event is regulated
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 HIV infection
Authored
Reviewed
Created