Reactome | LEPREL2 [endoplasmic reticulum lumen]

LEPREL2 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-1650821

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Prolyl 3-hydroxylase 3, P3H3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8IVL6 P3H3

Gene Names

P3H3, LEPREL2

Chain

signal peptide:1-20, chain:21-736

Reference Genes

BioGPS Gene:10536 P3H3

COSMIC (genes):P3H3 P3H3

CTD Gene:10536 P3H3

dbSNP Gene:10536 P3H3

ENSEMBL:ENSG00000110811 P3H3

HGNC:19318 P3H3

KEGG:hsa:10536 P3H3

Monarch:10536 P3H3

NCBI Gene:10536 P3H3

OMIM:610342 P3H3

UCSC:Q8IVL6 P3H3

Reference Transcript

RefSeq:NM_014262.4 P3H3

Participates

as a candidate of

Prolyl 3-hydroxylases [endoplasmic reticulum lumen] (Homo sapiens)

Inferred To

P3H3 [endoplasmic reticulum lumen] (Bos taurus)

P3H3 [endoplasmic reticulum lumen] (Canis familiaris)

Gpr162 [endoplasmic reticulum lumen] (Rattus norvegicus)

LEPREL2 [endoplasmic reticulum lumen] (Gallus gallus)

LEPREL2 [endoplasmic reticulum lumen] (Mus musculus)

Cross References

ENSEMBL

ENST00000290510, ENSP00000478600, ENSG00000110811

OpenTargets

ENSG00000110811

GeneCards

P3H3

HPA

ENSG00000110811-P3H3

PRO

Q8IVL6

Pharos - Targets

Q8IVL6

GlyGen

Q8IVL6

HMDB Protein

HMDBP08683

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q03405 PLAUR	7	GPI-PLAUR [specific granule membrane] (R-HSA-6806143) PLAUR [plasma membrane] (R-HSA-6806165) GPI-PLAUR [plasma membrane] (R-HSA-158946) PLAUR(23-335) [endoplasmic reticulum membrane] (R-HSA-162866) PLAUR(306-335) [endoplasmic reticulum lumen] (R-HSA-162707) GPI-PLAUR [endoplasmic reticulum membrane] (R-HSA-162687) PLAUR [endoplasmic reticulum membrane] (R-HSA-162703)	0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
UniProt:Q14145 KEAP1	3	KEAP1 [cytosol] (R-HSA-976038) ub-KEAP1 [cytosol] (R-HSA-9766647) Ub-KEAP1 [cytosol] (R-HSA-6782766)	0.527	2
UniProt:P48023 FASLG	1	FASLG(1-281) [extracellular region] (R-HSA-66212)	0.527	2

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