PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine

Stable Identifier
R-HSA-1655443
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cysteine sulfinic acid decarboxylase (CSAD) mediates the decarboxylase of 3-sulfinoalanine to produce hypotuarine. CSAD functions as a homodimer and requires pyridoxal phosphate as a cofactor. Purification, characterisation and activity of CSAD has been determined from rat liver (Guion-Rain et al. 1975).
Literature References
PubMed ID Title Journal Year
236774 Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties

Guion-Rain, M-C, Portemer, C, Chatagner, F

Biochim Biophys Acta 1975
Participants
Input
Output
Participates
as an event of
Catalyst Activity

sulfinoalanine decarboxylase activity of PXKLP-K305-CSAD dimer [cytosol]

Physical Entity
PXKLP-K305-CSAD dimer [cytosol] (Homo sapiens)
Activity
sulfinoalanine decarboxylase activity (GO:0004782)
Inferred From
PXLP-K305-Csad decarboxylates 3-sulfinoalanine to hypotaurine (Rattus norvegicus)
Cross References
Rhea
Authored
Jassal, B  (2011-10-12)
Reviewed
D'Eustachio, P  (2011-10-13)
Created
Jassal, B  (2011-10-12)
Cite Us!