MTOR [cytosol]

Stable Identifier
R-HSA-165662
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
mTOR
Icon
MTOR [cytosol] icon
MTOR [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P42345 MTOR
Gene Names
MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Chain
chain:1-2549
Reference Genes
BioGPS Gene:2475 MTOR
COSMIC (genes):MTOR MTOR
CTD Gene:2475 MTOR
dbSNP Gene:2475 MTOR
ENSEMBL:ENSG00000198793 MTOR
HGNC:3942 MTOR
KEGG Gene (Homo sapiens):2475 MTOR
Monarch:2475 MTOR
NCBI Gene:2475 MTOR
OMIM:601231 MTOR
UCSC:P42345 MTOR
Reference Transcript
Other Identifiers
0003190369
04150+2.7.11.1
04151+2.7.11.1
04714+2.7.11.1
04926+2.7.11.1
05163+2.7.11.1
05165+2.7.11.1
05170+2.7.11.1
11716133_a_at
11716134_a_at
11750567_a_at
16681661
1AUE
1FAP
1NSG
202288_at
2396538
2396539
2396540
2396541
2396542
2396543
2396544
2396545
2396547
2396548
2396550
2396552
2396555
2396556
2396557
2396560
2396561
2396562
2396563
2396565
2396567
2396569
2396570
2396571
2396572
2396576
2396577
2396580
2396581
2396582
2396584
2396586
2396587
2396588
2396589
2396598
2396599
2396600
2396603
2396604
2396605
2396606
2396607
2396609
2396610
2396611
2396612
2396613
2396614
2396615
2396616
2396617
2396618
2396619
2396620
2396622
2396623
2396625
2396628
2396629
2396633
2396635
2396637
2475
267_at
2FAP
2GAQ
2NPU
2RSE
3FAP
3JBZ
40139_at
4DRH
4DRI
4DRJ
4FAP
4JSN
4JSP
4JSV
4JSX
4JT5
4JT6
5FLC
5GPG
5H64
5WBH
5WBU
5WBY
5ZCS
69425
6BCU
6BCX
71227
7912412
A_23_P34606
AAA58486
AAC39933
AAC41713
AAI17167
AB209995
AJ300188
AL049653
AL109811
AL391561
B1AKP8
B1AKQ2
BAE06077
BC117166
CAB069425
CAC15570
CCDS127
ENSG00000198793
ENSP00000354558
ENST00000361445
ENST00000361445.8
EntrezGene:2475
EntrezGene:MTOR
g3282238_3p_at
GE81461
GO:0000003
GO:0000139
GO:0000166
GO:0001030
GO:0001031
GO:0001032
GO:0001156
GO:0001558
GO:0001932
GO:0001933
GO:0001934
GO:0001938
GO:0002296
GO:0002376
GO:0003007
GO:0003013
GO:0003179
GO:0003674
GO:0003677
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005764
GO:0005765
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005975
GO:0005979
GO:0006091
GO:0006109
GO:0006112
GO:0006207
GO:0006412
GO:0006464
GO:0006468
GO:0006629
GO:0006810
GO:0006914
GO:0006950
GO:0007010
GO:0007049
GO:0007050
GO:0007165
GO:0007267
GO:0007281
GO:0007420
GO:0007568
GO:0007569
GO:0007584
GO:0007616
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008361
GO:0008542
GO:0009056
GO:0009058
GO:0009267
GO:0009791
GO:0010506
GO:0010507
GO:0010592
GO:0010628
GO:0010718
GO:0010831
GO:0010942
GO:0010976
GO:0012505
GO:0014042
GO:0014736
GO:0014823
GO:0016020
GO:0016241
GO:0016242
GO:0016301
GO:0016310
GO:0016605
GO:0016740
GO:0018105
GO:0018107
GO:0019899
GO:0019901
GO:0019904
GO:0021510
GO:0021700
GO:0022607
GO:0030030
GO:0030154
GO:0030163
GO:0030425
GO:0030838
GO:0031090
GO:0031397
GO:0031529
GO:0031641
GO:0031667
GO:0031669
GO:0031929
GO:0031931
GO:0031932
GO:0031998
GO:0032095
GO:0032148
GO:0032516
GO:0032868
GO:0032956
GO:0032991
GO:0034198
GO:0034641
GO:0034655
GO:0035176
GO:0035264
GO:0038202
GO:0040007
GO:0040011
GO:0042060
GO:0042220
GO:0042752
GO:0042802
GO:0043022
GO:0043025
GO:0043087
GO:0043167
GO:0043200
GO:0043226
GO:0043231
GO:0043276
GO:0043278
GO:0043610
GO:0044281
GO:0044877
GO:0045182
GO:0045429
GO:0045670
GO:0045727
GO:0045792
GO:0045859
GO:0045945
GO:0046777
GO:0046889
GO:0048255
GO:0048511
GO:0048661
GO:0048714
GO:0048738
GO:0048856
GO:0048870
GO:0050731
GO:0050769
GO:0050877
GO:0050882
GO:0051219
GO:0051496
GO:0051549
GO:0051896
GO:0051897
GO:0055006
GO:0055013
GO:0055085
GO:0060048
GO:0060135
GO:0060252
GO:0060999
GO:0061051
GO:0065003
GO:0070885
GO:0071230
GO:0071233
GO:0071456
GO:0090335
GO:0090559
GO:0098978
GO:0099524
GO:0099547
GO:1900034
GO:1901216
GO:1901838
GO:1903691
GO:1904000
GO:1904056
GO:1904058
GO:1904059
GO:1904193
GO:1904197
GO:1904206
GO:1904213
GO:1904690
GO:1990253
HGNC:3942
HPA071227
ILMN_1769031
IPR000403
IPR003151
IPR003152
IPR009076
IPR011009
IPR011989
IPR011990
IPR014009
IPR016024
IPR018936
IPR024585
IPR026683
IPR036738
IPR036940
L34075
L34075_at
L35478
LRG_734
LRG_734t1
MIM:601231
MIM:607341
MIM:616638
MTOR
MTOR-201
NM_004958
NP_004949
PF00454
PF02259
PF02260
PF08771
PF11865
PH_hs_0016579
SM00146
SM01343
SM01345
SM01346
TC01002197.hg
U88966
UPI000012ABD3
XM_005263438
XM_017000900
XM_017000901
XM_024446187
XP_005263495
XP_016856389
XP_016856390
XP_024301955
XR_001737087
Participant Of
hasComponent
Other forms of this molecule
MTOR [nucleoplasm]
Inferred To
MTOR [cytosol] (Bos taurus)
MTOR [cytosol] (Canis familiaris)
MTOR [cytosol] (Gallus gallus)
MTOR [cytosol] (Sus scrofa)
Homologues of MTOR [cytosol] (Xenopus tropicalis)
tor2 [cytosol] (Schizosaccharomyces pombe)
TOR2 [cytosol] (Saccharomyces cerevisiae)
Tor [cytosol] (Drosophila melanogaster)
tor [cytosol] (Dictyostelium discoideum)
let-363 [cytosol] (Caenorhabditis elegans)
pde6a [cytosol] (Xenopus tropicalis)
mtor [cytosol] (Danio rerio)
mtor [cytosol] (Xenopus tropicalis)
Mtor [cytosol] (Mus musculus)
Mtor [cytosol] (Rattus norvegicus)
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
PRO
PDB
ZINC - Investigational
HPA
GeneCards
Ensembl
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62942 FKBP1A  1 0.807 5
 UniProt:P31749 AKT1  13 0.744 4
 UniProt:O75385 ULK1  7 0.702 7
 UniProt:Q12933 TRAF2  5 0.589 2
 UniProt:Q96B36 AKT1S1  5 0.564 2
 UniProt:Q96EB6 SIRT1  1 0.525 2