mTORC1 phosphorylation of RPS6KB1 (S6K)

Stable Identifier
R-HSA-165718
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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RPS6KB1 (S6K1) contains a TOS motif. mTORC1 requires an intact TOS motif to bind and phosphorylate S6K1 (Ali & Sabatini 2005).

Literature References
PubMed ID Title Journal Year
15809305 Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR

Ali, SM, Sabatini, DM

J Biol Chem 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of Active mTORC1 complex [lysosomal membrane]
Physical Entity
Activity
This event is regulated
Orthologous Events
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Reviewed
Created