PIPs transport between early and late endosome membranes

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R-HSA-1660502
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Pathway
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Homo sapiens
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The maturation of the early endosome compartment into a late endosome is triggered by the presence of phosphoinositide phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) (Cabezas et al. 2006, Ikonomov et al. 2006, Ikonomov et al. 2001).

Literature References
PubMed ID Title Journal Year
16510848 Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion

Ikonomov, OC, Sbrissa, D, Shisheva, A

Am J Physiol Cell Physiol 2006
11285266 Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

Ikonomov, OC, Sbrissa, D, Shisheva, A

J Biol Chem 2001
16448788 Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1

Cabezas, A, Pattni, K, Stenmark, H

Gene 2006
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