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MyrG-p-S16-TICAM2 [plasma membrane]
Stable Identifier
R-HSA-166160
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
TRAM
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
MyrG-p-S16-TICAM2 [plasma membrane] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
Endocytosis of TRAM (TICAM2) (Homo sapiens)
MyrG-p-S16-TICAM2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86XR7 TICAM2
Gene Names
TICAM2, TIRAP3, TIRP, TRAM
Chain
initiator methionine:, chain:2-235
Reference Genes
BioGPS Gene:100302736 TICAM2
BioGPS Gene:353376 TICAM2
COSMIC (genes):TICAM2 TICAM2
CTD Gene:100302736 TICAM2
CTD Gene:353376 TICAM2
dbSNP Gene:100302736 TICAM2
dbSNP Gene:353376 TICAM2
ENSEMBL:ENSG00000243414 TICAM2
ENSEMBL_homo_sapiens_GENE:ENSG00000243414.6 TICAM2
HGNC:21354 TICAM2
KEGG Gene (Homo sapiens):100302736 TICAM2
KEGG Gene (Homo sapiens):353376 TICAM2
Monarch:100302736 TICAM2
Monarch:353376 TICAM2
NCBI Gene:100302736 TICAM2
NCBI Gene:353376 TICAM2
OMIM:608321 TICAM2
UCSC:Q86XR7 TICAM2
Reference Transcript
RefSeq:NM_001164468.3 TICAM2
RefSeq:NM_001164469.3 TICAM2
RefSeq:NM_021649.7 TICAM2
Other Identifiers
11730553_a_at
11745544_a_at
11758448_s_at
228234_PM_at
228234_at
239431_PM_at
239431_at
2871828
2871829
2871830
2871831
2871832
2871833
2871834
2871835
2871836
2871837
2871846
2871847
2871848
2871849
353376
61865_at
85251_at
A_33_P3327270
GE62694
GO:0001891
GO:0002376
GO:0002735
GO:0005515
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005783
GO:0005794
GO:0005886
GO:0006909
GO:0006954
GO:0007165
GO:0010008
GO:0016020
GO:0016192
GO:0019901
GO:0023052
GO:0030667
GO:0031410
GO:0031663
GO:0031901
GO:0031902
GO:0032481
GO:0032816
GO:0034142
GO:0034145
GO:0035666
GO:0035669
GO:0042995
GO:0043123
GO:0043226
GO:0043330
GO:0045087
GO:0060090
GO:0071222
GO:0071651
GO:0098542
GO:1900017
GO:2000494
HMNXSV003015098
Hs.114055.0.A1_3p_at
Hs.184418.0.A1_3p_at
ILMN_1651346
PH_hs_0034823
Participates
as a member of
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
as an input of
Endocytosis of TRAM (TICAM2) (Homo sapiens)
Other forms of this molecule
MyrG-p-S16-TICAM2 [secretory granule membrane]
MyrG-p-S16-TICAM2 [endosome membrane]
Inferred To
phospho-ticam1 [plasma membrane]
(Danio rerio)
phospho-TICAM2 [plasma membrane]
(Bos taurus)
phospho-TICAM2 [plasma membrane]
(Canis familiaris)
phospho-TICAM2 [plasma membrane]
(Sus scrofa)
phospho-Ticam2 [plasma membrane]
(Mus musculus)
phospho-Ticam2 [plasma membrane]
(Rattus norvegicus)
Modified Residues
Name
N-myristoylglycine at 2
Coordinate
2
PsiMod Name
N-myristoylglycine [MOD:00068]
PsiMod Definition
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
Name
O-phospho-L-serine at 16
Coordinate
16
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001157941.1
,
NP_067681.1
,
NP_001157940.1
OpenTargets
ENSG00000243414
GeneCards
Q86XR7
HPA
ENSG00000243414-TICAM2
Ensembl
ENSG00000243414
,
ENSP00000415139
,
ENST00000427199
PRO
Q86XR7
Pharos - Targets
Q86XR7
PDB
2M1W
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00206 TLR4
2
TLR4 [endosome membrane]
(R-HSA-2201285)
2xN4GlycoAsn-TLR4 [plasma membrane]
(R-HSA-166045)
0.678
3
UniProt:Q6SZW1 SARM1
0.592
2
UniProt:P50222 MEOX2
0.556
3
UniProt:Q96HA8 NTAQ1
0.556
3
UniProt:P0C6I1-PRO_0000324727 C
0.463
2
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