p-4S,T404-IRF3 [cytosol]

Stable Identifier
R-HSA-166258
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-T,4S-IRF3
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q14653 IRF3
Gene Names
IRF3
Chain
chain:1-427
Reference Genes
BioGPS Gene:3661 IRF3
COSMIC (genes):IRF3 IRF3
CTD Gene:3661 IRF3
dbSNP Gene:3661 IRF3
ENSEMBL:ENSG00000126456 IRF3
HGNC:6118 IRF3
KEGG Gene (Homo sapiens):3661 IRF3
Monarch:3661 IRF3
NCBI Gene:3661 IRF3
OMIM:603734 IRF3
UCSC:Q14653 IRF3
Reference Transcript
Other Identifiers
0002030056
11718672_x_at
11745498_a_at
11745499_x_at
11753805_a_at
11753806_x_at
11756572_x_at
13018
16874347
1J2F
1QWT
1T2K
1ZOQ
202621_at
2O61
2O6G
2PI0
3661
371_at
3867989
3867990
3867991
3867993
3867995
3867996
3867997
3867998
3867999
3868000
3868001
3868002
3868003
3868007
3868008
3868009
3868010
3868011
3868012
3A77
3QU6
4895
5JEJ
5JEK
5JEL
5JEM
5JEO
5JER
8038416
A_23_P27677
A_33_P3327333
AAC68818
AAH00660
AAH71721
AB102884
AB102886
AB102887
AC011495
AK292027
AK314421
BAD89413
BAD89415
BAD89416
BAF84716
BAG37040
BC000660
BC071721
CAA91227
CAB013018
CCDS12775
CCDS56099
CCDS59407
CCDS59409
CH471177
EAW52510
ENSG00000126456
ENSP00000310127
ENSP00000366344
ENSP00000400378
ENSP00000469113
ENSP00000470512
ENSP00000471358
ENSP00000471896
ENSP00000472700
ENST00000309877
ENST00000309877.11
ENST00000377139
ENST00000377139.7
ENST00000442265
ENST00000442265.2
ENST00000596765
ENST00000596765.5
ENST00000597198
ENST00000597198.5
ENST00000599223
ENST00000599223.5
ENST00000600022
ENST00000600022.5
ENST00000601291
ENST00000601291.5
EntrezGene:3661
EntrezGene:IRF3
g4504724_3p_at
g4504724_3p_x_at
GE60425
GO:0000122
GO:0000228
GO:0000790
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0002376
GO:0003674
GO:0003677
GO:0003700
GO:0003712
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006355
GO:0006366
GO:0006810
GO:0006915
GO:0006950
GO:0006974
GO:0007165
GO:0008150
GO:0008219
GO:0009058
GO:0009617
GO:0010468
GO:0015031
GO:0016032
GO:0019904
GO:0031663
GO:0032479
GO:0032480
GO:0032481
GO:0032496
GO:0032727
GO:0032728
GO:0034641
GO:0035666
GO:0039530
GO:0042802
GO:0042803
GO:0043123
GO:0043226
GO:0043330
GO:0043565
GO:0044212
GO:0044403
GO:0045087
GO:0045351
GO:0045893
GO:0045944
GO:0050715
GO:0050727
GO:0051607
GO:0060333
GO:0060337
GO:0060340
GO:0071222
GO:0071360
GO:0071888
GO:0097300
HGNC:6118
HPA004895
ILMN_1765649
IPR001346
IPR008984
IPR017855
IPR019471
IPR019817
IPR036388
IPR036390
IRF3
IRF3-201
IRF3-203
IRF3-204
IRF3-213
IRF3-217
IRF3-223
IRF3-225
IRF3-228
M0QX56
M0QXC8
M0QYT9
M0QYX3
M0QZB7
M0QZB8
M0R007
M0R0R8
M0R0X9
M0R205
M0R3C2
M0R3E9
MIM:603734
MIM:616532
NM_001197122
NM_001197123
NM_001197124
NM_001197127
NM_001197128
NM_001571
NP_001184051
NP_001184052
NP_001184053
NP_001184056
NP_001184057
NP_001562
NR_045568
PF00605
PF10401
PH_hs_0004298
PR00267
SM00348
SM01243
TC19001722.hg
U86636
UPI000012D88A
UPI000013CBFE
UPI0000202963
UPI00004CA0D9
UPI00004CA0DB
XM_006723197
XM_006723198
XM_006723200
XM_017026766
XM_017026767
XM_024451492
XM_024451493
XP_006723260
XP_006723261
XP_006723263
XP_016882255
XP_016882256
XP_024307260
XP_024307261
XR_001753678
XR_002958311
Z56281
Z56281_at
Participant Of
hasMember
hasComponent
output
input
Other forms of this molecule
p-5S,T404-IRF3 [nucleoplasm]
p-4S,T404-IRF3 [nucleoplasm]
IRF3 [cytosol]
Inferred To
phospho-p-4S,T404-IRF3 [cytosol] (Bos taurus)
phospho-p-4S,T404-IRF3 [cytosol] (Canis familiaris)
phospho-p-4S,T404-IRF3 [cytosol] (Danio rerio)
phospho-p-4S,T404-IRF3 [cytosol] (Mus musculus)
phospho-p-4S,T404-IRF3 [cytosol] (Rattus norvegicus)
phospho-p-4S,T404-IRF3 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-serine at 396
Coordinate
396
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 398
Coordinate
398
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 402
Coordinate
402
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 405
Coordinate
405
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 404
Coordinate
404
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (10)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q14653 IRF3  4 0.965 16
 UniProt:Q92793 CREBBP  3 0.899 10
 UniProt:Q9UHD2 TBK1  6 0.886 9
 UniProt:O14730 RIOK3  1 0.612 6
 UniProt:Q9Y5Q3 MAFB  1 0.556 4
 UniProt:Q14164 IKBKE  5 0.544 2
 UniProt:O43765 SGTA  1 0.543 3
 UniProt:Q9Y3R0 GRIP1  2 0.508 2
 UniProt:P06400 RB1  3 0.499 2
 UniProt:P28749 RBL1  2 0.499 2