The receptor:G-protein complex binds GTP

Stable Identifier
R-HSA-167429
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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The receptor:G-protein complex binds GTP
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The ternary complex neurotransmitter:receptor:G-protein binds GTP, resulting in activation of G protein.

Literature References
PubMed ID Title Journal Year
16892066 Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

Preininger, AM, Hubbell, WL, Van Eps, N, Oldham, WM, Hamm, HE

Nat Struct Mol Biol 2006
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Output
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as an event of
Catalyst Activity

GTP binding activity of G-protein alpha (q/11/14/15) [plasma membrane]

Physical Entity
G-protein alpha (q/11/14/15) [plasma membrane] (Homo sapiens)
Activity
GTP binding (GO:0005525)
Orthologous Events
The receptor:G-protein complex binds GTP (Bos taurus)
The receptor:G-protein complex binds GTP (Caenorhabditis elegans)
The receptor:G-protein complex binds GTP (Canis familiaris)
The receptor:G-protein complex binds GTP (Danio rerio)
The receptor:G-protein complex binds GTP (Gallus gallus)
The receptor:G-protein complex binds GTP (Mus musculus)
The receptor:G-protein complex binds GTP (Rattus norvegicus)
The receptor:G-protein complex binds GTP (Sus scrofa)
The receptor:G-protein complex binds GTP (Xenopus tropicalis)
Authored
Jassal, B  (2004-03-31)
Le Novere, N  (2004-03-31)
Reviewed
Castagnoli, L  (2008-11-06)
Created
Jassal, B  (2005-10-18)
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