Reactome | PI4KB binds to ARF1/3:GTP at the Golgi membrane

PI4KB binds to ARF1/3:GTP at the Golgi membrane

Stable Identifier

R-HSA-1676152

Type

Reaction [binding]

Species

Homo sapiens

Compartment

Golgi membrane, cytosol

ReviewStatus

5/5

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PI4KB binds to ARF1/3:GTP at the Golgi membrane

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At the Golgi membrane, ADP-ribosylation factor 1 and 3 (ARF1 and ARF3) complexed to GTP bind to phosphatidylinositol 4-kinase beta (PI4KB) and activate it (Haynes et al. 2007, Wong et al. 1997, Godi et al. 1999).

Literature References

PubMed ID	Title	Journal	Year
9148941	Subcellular locations of phosphatidylinositol 4-kinase isoforms Cantley, LC, Meyers, ddR, Wong, K	J Biol Chem	1997
10559940	ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex Corda, D, Luini, A, Di Tullio, G, Godi, A, Iurisci, C, Pertile, P, Meyers, R, De Matteis, MA, Marra, P	Nat Cell Biol	1999
17555535	Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta Burgoyne, RD, Sherwood, MW, Dolman, NJ, Haynes, LP	Traffic	2007