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EIF4G2 [cytosol]
Stable Identifier
R-HSA-1678826
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Eukaryotic translation initiation factor 4 gamma 2, IF4G2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
Competitive inhibition of translation initiation by ISGylated 4EHP (Homo sapiens)
EIF4F [cytosol] (Homo sapiens)
EIF4G [cytosol] (Homo sapiens)
EIF4G2 [cytosol] (Homo sapiens)
eIF4F:mRNA [cytosol] (Homo sapiens)
EIF4F [cytosol] (Homo sapiens)
EIF4G [cytosol] (Homo sapiens)
EIF4G2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P78344 EIF4G2
Gene Names
EIF4G2, DAP5, OK/SW-cl.75
Chain
chain:1-907
Reference Genes
BioGPS Gene:1982 EIF4G2
COSMIC (genes):EIF4G2 EIF4G2
CTD Gene:1982 EIF4G2
dbSNP Gene:1982 EIF4G2
ENSEMBL:ENSG00000110321 EIF4G2
HGNC:3297 EIF4G2
KEGG:hsa:1982 EIF4G2
Monarch:1982 EIF4G2
NCBI Gene:1982 EIF4G2
OMIM:602325 EIF4G2
UCSC:P78344 EIF4G2
Reference Transcript
RefSeq:NM_001172705.1 EIF4G2
RefSeq:NM_001418.3 EIF4G2
RefSeq:NM_001042559.2 EIF4G2
Other Identifiers
11717092_s_at
11741083_x_at
11752094_a_at
11757168_at
11757169_x_at
1557964_PM_at
1557964_at
16653039
16653041
16653043
16653045
16653047
16653049
16653053
16653055
16653057
16653059
16653061
16653067
16653071
16735801
17118818
18671328
18671329
18671330
18671331
18671332
18671333
18671334
18671335
18671336
18671337
18671338
18671339
18671340
18671341
18671342
18671343
18671344
18671345
18671346
18671347
18671348
18671349
18671350
18671351
18671352
18671353
18671354
18671355
18671356
18671357
18671358
18671359
18671360
18671361
18671362
18671363
18671364
1982
200004_PM_at
200004_at
217607_PM_x_at
217607_x_at
3362733
3362734
3362735
3362736
3362737
3362738
3362739
3362740
3362741
3362742
3362743
3362744
3362745
3362746
3362747
3362748
3362749
3362750
3362751
3362752
3362753
3362754
3362755
3362756
3362757
3362758
3362759
3362760
3362761
3362762
3362763
3362764
3362765
3362766
3362767
3362768
3362769
3362770
3362771
3362772
3362773
3362774
3362775
3362776
3362777
3362778
3362779
3362780
3362781
3362782
3362783
3362784
3362785
3362786
3362787
3362788
3362789
3362790
3362791
3362792
41785_at
7892762
7892898
7892911
7893087
7893131
7893139
7893205
7893277
7893422
7893463
7893466
7893543
7893582
7893602
7893685
7893759
7893961
7894044
7894058
7894098
7894161
7894291
7894411
7894454
7894551
7894605
7894782
7894788
7895081
7895087
7895089
7895248
7895355
7895382
7895681
7895704
7895824
7895886
7895963
7896013
7896432
7946610
89110_at
A_21_P0000501
A_33_P3306545
GE61376
GO:0003723
GO:0003729
GO:0003743
GO:0005515
GO:0005829
GO:0005912
GO:0006412
GO:0006413
GO:0006417
GO:0006446
GO:0007507
GO:0008135
GO:0008219
GO:0009059
GO:0010507
GO:0016020
GO:0016281
GO:0030307
GO:0030424
GO:0045182
GO:0045296
GO:0045727
GO:0045773
GO:0048856
GO:0051726
GO:0060999
HMNXSV003009138
HMNXSV003022013
Hs.150904.0.S1_3p_at
Hs.150904.0.S1_3p_x_at
Hs2.190503.1.S1_3p_at
ILMN_1761519
ILMN_2279635
ILMN_2380946
PH_hs_0032048
RNA33438|snoRNA_scaRNA_34_142
TC11001417.hg
TC11001418.hg
TC11003053.hg
U73824_at
g4503538_3p_at
Participates
as a member of
EIF4G [cytosol] (Homo sapiens)
Inferred To
Homologues of EIF4G2 [cytosol]
(Plasmodium falciparum)
eif4g2 [cytosol]
(Xenopus tropicalis)
eif4g2a [cytosol]
(Danio rerio)
EIF4G2 [cytosol]
(Bos taurus)
EIF4G2 [cytosol]
(Canis familiaris)
EIF4G2 [cytosol]
(Gallus gallus)
EIF4G2 [cytosol]
(Plasmodium falciparum)
EIF4G2 [cytosol]
(Sus scrofa)
eif4g [cytosol]
(Dictyostelium discoideum)
Eif4g2 [cytosol]
(Mus musculus)
Eif4g2 [cytosol]
(Rattus norvegicus)
NAT1 [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001409.3
,
NP_001166176.1
,
NP_001036024.3
ENSEMBL
ENSP00000340281
,
ENSP00000433371
,
ENST00000526148
,
ENST00000525681
,
ENSP00000379778
,
ENST00000396525
,
ENSP00000433664
,
ENST00000339995
OpenTargets
ENSG00000110321
HPA
ENSG00000110321-EIF4G2
PRO
P78344
Pharos - Targets
P78344
GlyGen
P78344
PDB
3D3M
,
4IUL
,
3L6A
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
10
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.508
3
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.483
2
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