Reactome | UNC93B1 [endoplasmic reticulum membrane]

UNC93B1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1678930

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Unc93 homolog B1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9H1C4 UNC93B1

Gene Names

UNC93B1, UNC93, UNC93B

Chain

chain:1-597

Reference Genes

BioGPS Gene:81622 UNC93B1

CTD Gene:81622 UNC93B1

dbSNP Gene:81622 UNC93B1

ENSEMBL:ENSG00000110057 UNC93B1

HGNC:13481 UNC93B1

KEGG Gene (Homo sapiens):81622 UNC93B1

Monarch:81622 UNC93B1

NCBI Gene:81622 UNC93B1

OMIM:608204 UNC93B1

UCSC:Q9H1C4 UNC93B1

Reference Transcript

RefSeq:NM_030930.3 UNC93B1

Other Identifiers

0000130039

11721322_at

16741173

17100833

220998_s_at

225869_s_at

2683250

2683252

2718105

2718108

2718113

2758606

2758607

2758608

2758633

2758635

2758636

3037672

3037673

3037682

3339081

3339082

3339084

3379132

3379270

3379271

3379272

3379273

3379276

3379277

3379280

3379282

3379285

3379286

3379290

3379291

3379292

3379294

3379296

3379297

3379298

49533_at

78054_at

7949904

8094144

8138147

81622

A_23_P98167

A_33_P3262758

GE61081

GO:0000139

GO:0002224

GO:0002250

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005764

GO:0005768

GO:0005773

GO:0005783

GO:0005789

GO:0005794

GO:0006810

GO:0006886

GO:0006950

GO:0007165

GO:0008150

GO:0015031

GO:0016020

GO:0016021

GO:0031410

GO:0032009

GO:0034138

GO:0034154

GO:0034162

GO:0035325

GO:0043226

GO:0045087

GO:0045335

GO:0051607

Hs.135187.1.A1_3p_s_at

ILMN_1654812

ILMN_2193591

PH_hs_0027846

TC11001999.hg

g13569892_3p_s_at

Participant Of

input

Full-length TLR3/7/8/9 binds to UNC93B1

hasComponent

intracellular TLR:UNC93B1 [endoplasmic reticulum membrane]

Other forms of this molecule

UNC93B1 [Golgi membrane]

UNC93B1 P345fs* [endoplasmic reticulum membrane]

UNC93B1 G261fs* [endoplasmic reticulum membrane]

Inferred To

Unc93b1 [endoplasmic reticulum membrane] (Mus musculus)

Unc93b1 [endoplasmic reticulum membrane] (Rattus norvegicus)

UNC93B1 [endoplasmic reticulum membrane] (Bos taurus)

UNC93B1 [endoplasmic reticulum membrane] (Canis familiaris)

UNC93B1 [endoplasmic reticulum membrane] (Gallus gallus)

UNC93B1 [endoplasmic reticulum membrane] (Sus scrofa)

unc93b1 [endoplasmic reticulum membrane] (Danio rerio)

unc93b1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_112192.2

OpenTargets

ENSG00000110057

HPA

ENSG00000110057-UNC93B1

GeneCards

Q9H1C4

Ensembl

ENST00000227471, ENSG00000110057, ENSP00000227471

PRO

Q9H1C4

Orphanet

15695

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H7V2 SYNG1			0.556	3
UniProt:Q5T700 LRAD1			0.556	3
UniProt:P11912 CD79A	2	CD79A [plasma membrane] (R-HSA-197154) p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539)	0.556	3
UniProt:Q9GZY8-5 MFF			0.556	3
UniProt:A8MZ59 LEUTX			0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:O14843 FFAR3	1	FFAR3 [plasma membrane] (R-HSA-443951)	0.556	3
UniProt:P26715 KLRC1	1	KLRC1 [plasma membrane] (R-HSA-3006545)	0.556	3
UniProt:O60883 GPR37L1	1	GPR37L1 [plasma membrane] (R-HSA-5336178)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q9UM44 HHLA2			0.556	3
UniProt:Q8NFU1 BEST2	1	BEST2 [plasma membrane] (R-HSA-2744359)	0.556	3
UniProt:Q969F0 FATE1			0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	3
UniProt:Q9H902 REEP1	1	REEP1 [endoplasmic reticulum membrane] (R-HSA-8939766)	0.556	3
UniProt:Q96P66 GP101			0.556	3
UniProt:Q96CE8 T4S18			0.556	3
UniProt:O95471 CLDN7	2	CLDN7 [cell junction] (R-HSA-421241) CLDN7 [plasma membrane] (R-HSA-420004)	0.556	3
IntAct:EBI-23184686 CCSB ORF ID			0.556	3
UniProt:Q8WV48 CC107			0.556	3
UniProt:Q9H400 LIME1			0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q9NQQ7-3 Q9NQQ73			0.556	3
UniProt:Q9NZD1 GPC5D			0.556	3
UniProt:Q8WWF3 SSMM1			0.556	3
UniProt:P37268 FDFT1	1	FDFT1 [endoplasmic reticulum membrane] (R-HSA-191369)	0.527	2
UniProt:P55060 XPO2			0.499	2
UniProt:Q14974 KPNB1	5	KPNB1 [nucleoplasm] (R-HSA-180714) KPNB1 [cytosol] (R-HSA-180733) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [specific granule lumen] (R-HSA-6799646)	0.499	2
UniProt:Q9NR97 TLR8	4	TLR8 [endoplasmic reticulum membrane] (R-HSA-1678947) TLR8 [endosome membrane] (R-HSA-1679577) TLR8 [endolysosome membrane] (R-HSA-167927) TLR8 [Golgi membrane] (R-HSA-1678918)	0.463	3

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