Reactome | ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane]

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1679076

Type

Complex

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
20865800	Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone Liu, B, Yang, Y, Qiu, Z, Staron, M, Hong, F, Li, Y, Wu, S, Li, Y, Hao, B, Bona, R, Han, D, Li, Z	Nat Commun	2010

Participants

components

Participant Of

output

TLR folding by chaperones GP96 and CNPY3

input

Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex

Inferred To

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] (Canis familiaris)

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] (Danio rerio)

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] (Gallus gallus)

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] (Mus musculus)

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] (Rattus norvegicus)

ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] (Sus scrofa)

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