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Release of the RNP into the host cell nucleus
Stable Identifier
R-HSA-168310
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
nucleoplasm
ReviewStatus
5/5
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)
Release of the RNP into the host cell nucleus (Homo sapiens)
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Once the viral RNP and heterodimeric karyopherin complex has been transported into the nucleus the RNP dissasociates from the heterodimeric karyopherins.
Literature References
PubMed ID
Title
Journal
Year
7559393
Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import
Moroianu, J
,
Blobel, G
,
Palese, P
,
Jaskunas, R
,
O'Neill, RE
J Biol Chem
1995
Participants
Input
RNP:Karyopherin alpha:Karyopherin beta complex [nucleoplasm]
(Homo sapiens)
Output
KPNA1 [nucleoplasm]
(Homo sapiens)
KPNB1 [nucleoplasm]
(Homo sapiens)
Ribonucleoprotein (RNP) Complex [nucleoplasm]
(Influenza A virus)
Participates
as an event of
Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)
Event Information
Go Biological Process
intracellular transport of virus (0075733)
Disease
Name
Identifier
Synonyms
influenza
DOID:8469
Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Gillespie, ME (2005-11-14)
Reviewed
Squires, B (2006-10-29)
Created
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