Influenza virus's non-structural protein (NS1) binds to the host cell's cleavage and host polyadenylation specificity factor (CPSF), inhibiting the ability of CPSF to bind to pre-mRNAs and thus preventing efficient 3' end processing and export of host cell mRNAs out of the nucleus.
Shimizu, K, Iguchi, A, Gomyou, R, Ono, Y
Li, Y, Chen, ZY, Wang, W, Baker, CC, Krug, RM
Noah, DL, Twu, KY, Krug, RM
Nemeroff, ME, Barabino, SM, Li, Y, Keller, W, Krug, RM
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