NA activation of TGF-beta

Stable Identifier
R-HSA-168865
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
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Influenza A virus induces apoptosis in a variety of ways including by activation of host TGF-beta by viral neuraminidase (NA).

Literature References
PubMed ID Title Journal Year
25535343 Influenza viral neuraminidase primes bacterial coinfection through TGF-β-mediated expression of host cell receptors

Li, N, Ren, A, Wang, X, Fan, X, Zhao, Y, Gao, GF, Cleary, P, Wang, B

Proc. Natl. Acad. Sci. U.S.A. 2015
9934696 Role of neuraminidase in influenza virus-induced apoptosis

Morris, SJ, Price, GE, Barnett, JM, Hiscox, SA, Smith, H, Sweet, C

J Gen Virol 1999
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
peptidase activator activity of NA [extracellular region]
Physical Entity
Activity
Disease
Name Identifier Synonyms
influenza 8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Reviewed
Created
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