Binding of NEP/NS2 to vRNP:M1

Stable Identifier
R-HSA-168893
Type
Reaction
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
Locations in the PathwayBrowser
Summation

Structural characterization of NEP/NS2 suggests that acidic residues in the C-terminus of NEP/NS2 bind to M1, with Trp78 critical for interaction (Ward, 1995; Yasuda, 1993; Akarsu, 2003).

Literature References
PubMed ID Title Journal Year
8356796 Molecular assembly of influenza virus: association of the NS2 protein with virion matrix

Yasuda, J, Nakada, S, Kato, A, Toyoda, T, Ishihama, A

Virology 1993
7503702 Expression and analysis of the NS2 protein of influenza A virus

Ward, AC, Castelli, LA, Lucantoni, AC, White, JF, Azad, AA, Macreadie, IG

Arch Virol 1995
Participants
Participant Of
Event Information
Disease
Name Identifier Synonyms
influenza 8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Reviewed