TICAM1, RIP1-mediated IKK complex recruitment

Stable Identifier
R-HSA-168927
Type
Pathway
Species
Homo sapiens
Related Species
Rotavirus, Influenza A virus, Hepatitis B virus, Hepatitis C Virus, Human herpesvirus 1
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Summation

Receptor-interacting protein 1 (RIP1) mediates the activation of interferon-alpha/beta via intermediate activation of IKK/TBK1 or NFkB pathways.

Literature References
PubMed ID Title Journal Year
15064760 RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B

Meylan, E, Burns, K, Hofmann, K, Blancheteau, V, Martinon, F, Kelliher, M, Tschopp, J

Nat Immunol 2004
16115877 Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

Cusson-Hermance, N, Khurana, S, Lee, TH, Fitzgerald, KA, Kelliher, MA

J Biol Chem 2005
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