Ligand binds to TLR10

Stable Identifier
R-HSA-168947
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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Ligand binds to TLR10
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Microbal stimulation was shown to alter mRNA expression of TLR10 in human granulocytes, monocytes[Zarember KA and Godowski P 2002] and B cells[Bourke ED et al 2003]. However the natural ligand of TLR10 remains unknown.

Literature References
PubMed ID Title Journal Year
15728506 Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88

Merck, E, Chaffois, C, Trinchieri, G, Vlach, J, Saulnier, V, Hasan, U, Lebecque, S, Briere, F, Bates, EE, Tancredi, S, Guiet, C, Gaillard, C

J Immunol 2005
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Authored
Luo, F  (2005-11-10)
Reviewed
Gillespie, ME  (2011-02-10)
Gale M, Jr  (2006-10-31)
Created
de Bono, B  (2005-11-22)
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