Reactome: A Curated Pathway Database

Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm

Stable Identifier
R-HSA-170072
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

During interphase, cyclin B1 shuttles continuously in and out of the nucleus. The cyclin B cytoplasmic retention sequence (CRS), which is responsible for its interphase cytoplasmic localization, functions as a nuclear export sequence (Yang et al., 1998).

Literature References
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Orthologous Events