Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases

Stable Identifier
R-HSA-170153
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Following its translocation to the nucleus, Cdc25 dephosphorylates and activates nuclear cyclin B1:Cdc2 complexes (Strausfeld et al., 1991).

Literature References
PubMed ID Title Journal Year
1828290 Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

Strausfeld, U, Labbe, JC, Fesquet, D, Cavadore, JC, Picard, A, Sadhu, K, Russell, P, Doree, M

Nature 1991
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
phosphoprotein phosphatase activity of CDC25 [nucleoplasm]
Physical Entity
Activity
Orthologous Events