Dissociation of the Gi alpha:G olf complex

Stable Identifier
R-HSA-170674
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Once the intrinsic GTPase hydrolyzes GTP to GDP, Galpha-i dissociates from adenylate cyclase, allowing it to re-associate with G-beta-gamma and starting a new cycle.
Literature References
PubMed ID Title Journal Year
7937899 Mechanism of GTP hydrolysis by G-protein alpha subunits

Kleuss, C, Gilman, AG, Sprang, SR, Raw, AS, Lee, E

Proc Natl Acad Sci U S A 1994
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!