Formation of the active cofactor, UDP-glucuronate

Stable Identifier
R-HSA-173599
Type
Pathway
Species
Homo sapiens
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Formation of the active cofactor, UDP-glucuronate
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Glucose 1-phosphate and UTP are the precursors to UDP-glucuronate formation. After oxidation of the resultant complex, UDP-glucuronate is transported to the ER lumen.

Literature References
PubMed ID Title Journal Year
17482904 Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification

Iyanagi, T

Int Rev Cytol 2007
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Events
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as an event of
Event Information
Go Biological Process
UDP-glucuronate biosynthetic process (0006065)
Orthologous Events
Formation of the active cofactor, UDP-glucuronate (Bos taurus)
Formation of the active cofactor, UDP-glucuronate (Caenorhabditis elegans)
Formation of the active cofactor, UDP-glucuronate (Canis familiaris)
Formation of the active cofactor, UDP-glucuronate (Danio rerio)
Formation of the active cofactor, UDP-glucuronate (Dictyostelium discoideum)
Formation of the active cofactor, UDP-glucuronate (Drosophila melanogaster)
Formation of the active cofactor, UDP-glucuronate (Gallus gallus)
Formation of the active cofactor, UDP-glucuronate (Mus musculus)
Formation of the active cofactor, UDP-glucuronate (Rattus norvegicus)
Formation of the active cofactor, UDP-glucuronate (Saccharomyces cerevisiae)
Formation of the active cofactor, UDP-glucuronate (Schizosaccharomyces pombe)
Formation of the active cofactor, UDP-glucuronate (Sus scrofa)
Formation of the active cofactor, UDP-glucuronate (Xenopus tropicalis)
Authored
Jassal, B  (2004-11-30)
Created
Jassal, B  (2006-02-14)
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