Reactome | C9(22-559) [extracellular region]

C9(22-559) [extracellular region]

Stable Identifier

R-HSA-173717

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P02748 C9

Gene Names

Chain

signal peptide:1-21, chain:22-559, chain:22-265, chain:266-559

Reference Genes

BioGPS Gene:735 C9

COSMIC (genes):C9 C9

CTD Gene:735 C9

dbSNP Gene:735 C9

ENSEMBL:ENSG00000113600 C9

HGNC:1358 C9

KEGG:hsa:735 C9

Monarch:735 C9

NCBI Gene:735 C9

OMIM:120940 C9

UCSC:P02748 C9

Reference Transcript

RefSeq:NM_001737.4 C9

Other Identifiers

11739817_at

11739818_at

16995629

206727_PM_at

206727_at

2854410

2854411

2854412

2854413

2854419

2854420

2854421

2854423

2854424

2854425

2854426

2854427

2854428

2854429

2854432

2854433

2854437

2854438

2854439

2854444

35526_at

735

8111757

A_32_P203917

GE57539

GO:0001906

GO:0002376

GO:0005515

GO:0005576

GO:0005579

GO:0005615

GO:0005886

GO:0006955

GO:0006956

GO:0006957

GO:0006958

GO:0016020

GO:0031640

GO:0043226

GO:0044218

GO:0050778

GO:0051260

GO:0065003

GO:0070062

GO:0072562

GO:0098542

HMNXSV003026008

Hs.1290.0.S2_3p_at

ILMN_1767831

K02766_at

PH_hs_0030867

TC05003424.hg

X02176_s_at

Participates

as a component of

as an input of

as a member of

C5b:C6:C7, C8, C9 [extracellular region] (Homo sapiens)

Inferred To

C9 [extracellular region] (Bos taurus)

C9 [extracellular region] (Canis familiaris)

C9 [extracellular region] (Mus musculus)

C9 [extracellular region] (Rattus norvegicus)

C9 [extracellular region] (Sus scrofa)

Cross References

ENSEMBL

ENST00000263408, ENSP00000263408, ENSG00000113600

OpenTargets

ENSG00000113600

GeneCards

HPA

ENSG00000113600-C9

PRO

P02748

Pharos - Targets

P02748

GlyGen

P02748

Orphanet

PDB

6H04, 7NYD, 8B0G, 7NYC, 5FMW, 6DLW, 8DE6, 8B0H, 6H03

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02649 APOE	10	APOE [extracellular region] (R-HSA-174646) APOE [endoplasmic reticulum lumen] (R-HSA-6784908) p-APOE [endoplasmic reticulum lumen] (R-HSA-8956980) APOE [endocytic vesicle lumen] (R-HSA-3221641) APOE-4 [extracellular region] (R-HSA-9711070) APOE [plasma membrane] (R-HSA-174615) APOE [clathrin-coated endocytic vesicle membrane] (R-HSA-174651) APOE [endosome membrane] (R-HSA-174766) APOE [endosome lumen] (R-HSA-174804) APOE [early endosome] (R-HSA-2429687)	0.564	2
UniProt:P00441 SOD1	5	SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [cytosol] (R-HSA-3299726) 2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [extracellular region] (R-HSA-350705)	0.556	3
UniProt:P01031 C5	7	C5a [extracellular region] (R-HSA-173677) C5 beta chain [extracellular region] (R-HSA-173675) C5 alpha chain [extracellular region] (R-HSA-173673) C5b alpha' [extracellular region] (R-HSA-173672) C5a-desArg [extracellular region] (R-HSA-8852798) C5aT [extracellular region] (R-HSA-8852711) C5(965-1676) [extracellular region] (R-HSA-8852713)	0.553	2

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