The degradation of cyclin B1, which appears to occur at the mitotic spindle, is delayed until the metaphase /anaphase transition by the spindle assembly checkpoint and is required in order for sister chromatids to separate (Geley et al. 2001;Hagting et al, 2002).
Geley, S, Kramer, E, Gieffers, C, Gannon, J, Peters, JM, Hunt, T
© 2021 Reactome