Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2

Stable Identifier
R-HSA-174110
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2
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Cdc25A, and probably Cdc25B, regulate the entry into S phase cell cycle by removing inhibitory phosphates from the Cdk2 subunit of Cyclin A:Cdk2.
Literature References
Participants
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Output
Participates
as an event of
Catalyst Activity

phosphoprotein phosphatase activity of Cdc25 A/B [nucleoplasm]

Physical Entity
Cdc25 A/B [nucleoplasm] (Homo sapiens)
Activity
phosphoprotein phosphatase activity (GO:0004721)
Orthologous Events
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Bos taurus)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Caenorhabditis elegans)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Canis familiaris)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Danio rerio)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Dictyostelium discoideum)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Drosophila melanogaster)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Gallus gallus)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Mus musculus)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Rattus norvegicus)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Schizosaccharomyces pombe)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Sus scrofa)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Xenopus tropicalis)
Authored
Pagano, M  (2006-09-19)
Reviewed
Coqueret, O  (2006-10-06)
Created
Matthews, L  (2006-02-17)
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