Association of Cyclin A with the APC/C

Stable Identifier
R-HSA-174171
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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General
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Cyclin A is believed to be recognized by the APC/C:Cdc20 complex through its D-box sequence, which is 10-20 residues longer than the D-box of cyclin B (Geley et al., 2001).

Literature References
PubMed ID Title Journal Year
10679238 Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex

Ohtoshi, A, Maeda, T, Higashi, H, Ashizawa, S, Hatakeyama, M

Biochem Biophys Res Commun 2000
11285280 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

Geley, S, Kramer, E, Gieffers, C, Gannon, J, Peters, JM, Hunt, T

J Cell Biol 2001
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created