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PSME2 [nucleoplasm]
Stable Identifier
R-HSA-174350
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Proteasome activator complex subunit 2, Proteasome activator 28-beta subunit, PA28beta, PA28b, Activator of multicatalytic protease subunit 2, 11S regulator complex beta subunit, REG-beta
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-12 family signaling (Homo sapiens)
Interleukin-12 signaling (Homo sapiens)
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)
Expression of Proteasome activator complex subunit 2 (Homo sapiens)
PSME2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UL46 PSME2
Gene Names
PSME2
Chain
initiator methionine:, chain:2-239
Reference Genes
BioGPS Gene:5721 PSME2
COSMIC (genes):PSME2 PSME2
CTD Gene:5721 PSME2
dbSNP Gene:5721 PSME2
ENSEMBL:ENSG00000100911 PSME2
HGNC:9569 PSME2
Monarch:5721 PSME2
NCBI Gene:5721 PSME2
OMIM:602161 PSME2
UCSC:Q9UL46 PSME2
Reference Transcript
RefSeq:NM_002818.2 PSME2
Other Identifiers
11758693_s_at
1184_at
16791059
201762_PM_s_at
201762_s_at
2749686
2749687
2821648
3238435
3489177
3489179
3489180
3489181
3489182
3557810
3557812
3557813
3557814
3557815
3557816
3557817
3557818
3557819
3557820
3557821
3557822
3557823
3557824
3557825
3557826
3557827
3557828
3557829
3557830
3557831
3557832
3557833
3557834
3557835
41171_at
5721
7978123
A_23_P65427
D45248_at
GE81197
GE86664
GO:0000502
GO:0005515
GO:0005654
GO:0005737
GO:0005829
GO:0008537
GO:0016020
GO:0042802
GO:0043226
GO:0061133
GO:0061136
GO:0070062
GO:0098772
GO:2000045
HMNXSV003006858
HMNXSV003016126
HMNXSV003036895
ILMN_1786612
PH_hs_0039146
PH_hs_0039739
TC13000192.hg
TC14000968.hg
g4506236_3p_a_at
Participates
as an output of
Expression of Proteasome activator complex subunit 2 (Homo sapiens)
Other forms of this molecule
PSME2 [cytosol]
Cross References
OpenTargets
ENSG00000100911
ENSEMBL
ENSP00000495790
,
ENSP00000216802
,
ENST00000216802
,
ENST00000645325
HPA
ENSG00000100911-PSME2
PRO
Q9UL46
Pharos - Targets
Q9UL46
GlyGen
Q9UL46
PDB
7DRW
,
7DR6
,
8CXB
,
7NAP
,
7NAO
Interactors (21)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q06323 PSME1
1
PSME1 [cytosol]
(R-HSA-68812)
0.801
10
UniProt:Q9UL46 PSME2
2
PSME2 [nucleoplasm]
(R-HSA-174350)
PSME2 [cytosol]
(R-HSA-68814)
0.718
6
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.706
13
UniProt:O00560 SDCBP
3
SDCBP [cytosol]
(R-HSA-373639)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [extracellular region]
(R-HSA-6806206)
0.666
5
UniProt:P49721 PSMB2
2
PSMB2 [cytosol]
(R-HSA-68744)
PSMB2 [nucleoplasm]
(R-HSA-174335)
0.643
4
UniProt:P28065 PSMB9
3
pro-PSMB9 [cytosol]
(R-HSA-9908136)
PSMB9 [cytosol]
(R-HSA-68765)
PSMB9(1-20) [cytosol]
(R-HSA-9908132)
0.643
5
UniProt:P20618 PSMB1
7
PSMB1 [cytosol]
(R-HSA-68738)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
0.643
5
UniProt:P25786 PSMA1
2
PSMA1 [cytosol]
(R-HSA-68724)
PSMA1 [nucleoplasm]
(R-HSA-174333)
0.629
8
UniProt:Q9BZL1 UBL5
1
UBL5 [nucleoplasm]
(R-HSA-9770255)
0.556
3
UniProt:Q9BVJ7 DUS23
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q99436 PSMB7
7
PSMB7 [cytosol]
(R-HSA-68759)
PSMB7 [nucleoplasm]
(R-HSA-174331)
PSMB7 [secretory granule lumen]
(R-HSA-6803279)
PSMB7 [extracellular region]
(R-HSA-6806449)
PSMB7 [ficolin-1-rich granule lumen]
(R-HSA-6803312)
pro-PSMB7 [cytosol]
(R-HSA-9908145)
PSMB7(1-43) [cytosol]
(R-HSA-9908129)
0.527
3
UniProt:P25787 PSMA2
5
PSMA2 [cytosol]
(R-HSA-68726)
PSMA2 [nucleoplasm]
(R-HSA-174345)
PSMA2 [secretory granule lumen]
(R-HSA-6803329)
PSMA2 [extracellular region]
(R-HSA-6806506)
PSMA2 [ficolin-1-rich granule lumen]
(R-HSA-6803285)
0.527
4
UniProt:P28066 PSMA5
5
PSMA5 [cytosol]
(R-HSA-68732)
PSMA5 [nucleoplasm]
(R-HSA-174340)
PSMA5 [secretory granule lumen]
(R-HSA-6803316)
PSMA5 [extracellular region]
(R-HSA-6806459)
PSMA5 [ficolin-1-rich granule lumen]
(R-HSA-6803328)
0.527
4
UniProt:P02675 FGB
5
FGB [extracellular region]
(R-HSA-140584)
FGB(31-44) [extracellular region]
(R-HSA-140876)
FGB [plasma membrane]
(R-HSA-140917)
FGB(31-491) [extracellular region]
(R-HSA-140846)
FGB(31-491) [platelet alpha granule lumen]
(R-HSA-140921)
0.527
2
UniProt:P28070 PSMB4
4
PSMB4 [cytosol]
(R-HSA-68750)
PSMB4 [nucleoplasm]
(R-HSA-174343)
pro-PSMB4 [cytosol]
(R-HSA-9908138)
PSMB4(1-45) [cytosol]
(R-HSA-9908122)
0.527
3
UniProt:Q9Y3I1 FBXO7
1
FBXO7 [cytosol]
(R-HSA-8862627)
0.527
2
UniProt:Q9BY78 RNF26
0.527
2
UniProt:P49720 PSMB3
2
PSMB3 [cytosol]
(R-HSA-68747)
PSMB3 [nucleoplasm]
(R-HSA-174341)
0.527
4
UniProt:Q8TCT7 SPPL2B
1
SPPL2B [plasma membrane]
(R-HSA-8863116)
0.527
2
UniProt:P40313 CTRL
1
pro-CTRL [zymogen granule]
(R-HSA-9922800)
0.527
2
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