Reactome | APOA5 [extracellular region]

APOA5 [extracellular region]

Stable Identifier

R-HSA-174608

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

apoA-V, apolipoprotein A-V

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6Q788 APOA5

Gene Names

APOA5, RAP3, UNQ411/PRO773

Chain

signal peptide:1-23, chain:24-366

Reference Genes

BioGPS Gene:116519 APOA5

COSMIC (genes):APOA5 APOA5

CTD Gene:116519 APOA5

dbSNP Gene:116519 APOA5

ENSEMBL:ENSG00000110243 APOA5

HGNC:17288 APOA5

KEGG Gene (Homo sapiens):116519 APOA5

Monarch:116519 APOA5

NCBI Gene:116519 APOA5

OMIM:606368 APOA5

UCSC:Q6Q788 APOA5

Reference Transcript

Other Identifiers

0002320398

116519

11735047_at

11756672_a_at

16744708

224243_at

224244_s_at

3392958

3392959

3392960

3392961

3392962

3392963

3392964

3392965

3392967

3392968

7951853

A_23_P75630

GE63051

GO:0003674

GO:0005543

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005768

GO:0005769

GO:0005770

GO:0005783

GO:0005788

GO:0005794

GO:0006464

GO:0006629

GO:0006641

GO:0006695

GO:0006810

GO:0006869

GO:0006950

GO:0008047

GO:0008150

GO:0008201

GO:0008289

GO:0009056

GO:0009058

GO:0010873

GO:0010898

GO:0010902

GO:0015485

GO:0016192

GO:0019216

GO:0019433

GO:0019899

GO:0022607

GO:0030234

GO:0030300

GO:0031210

GO:0031410

GO:0032991

GO:0033344

GO:0033700

GO:0034361

GO:0034364

GO:0034370

GO:0034372

GO:0034380

GO:0035473

GO:0040007

GO:0042157

GO:0042246

GO:0042592

GO:0042627

GO:0042632

GO:0043167

GO:0043226

GO:0043687

GO:0044267

GO:0044281

GO:0045723

GO:0046470

GO:0046889

GO:0048260

GO:0048856

GO:0050750

GO:0050996

GO:0051006

GO:0055090

GO:0060228

GO:0060229

GO:0060230

GO:0065003

GO:0070325

GO:0070328

ILMN_1754055

TC11002325.hg

g6707432_3p_at

g6707434_3p_a_at

Participant Of

output

Expression of APOA5

This entity regulates

Positively

chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols

Other forms of this molecule

APOA5 [cytosol]

p-APOA5 [endoplasmic reticulum lumen]

APOA5 [endoplasmic reticulum lumen]

Inferred To

Apoa5 [extracellular region] (Mus musculus)

Apoa5 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_001160070.1, NP_443200.2, XP_016872658.1

OpenTargets

ENSG00000110243

GeneCards

Q6Q788

HPA

ENSG00000110243-APOA5

Ensembl

ENST00000227665, ENSP00000227665, ENSP00000445002, ENSG00000110243, ENST00000542499

PRO

Q6Q788

Orphanet

15937

HMDB Protein

HMDBP10986

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:A0PK00 T120B			0.556	3
UniProt:Q96HH6 TMM19			0.556	3
UniProt:O95393 BMP10	2	BMP10 [extracellular region] (R-HSA-8858374) BMP10(22-424) [extracellular region] (R-HSA-2396409)	0.556	3
UniProt:Q9BTV4 TMM43			0.556	3
UniProt:Q9NX76 CMTM6	3	CMTM6 [plasma membrane] (R-HSA-6806275) CMTM6 [specific granule membrane] (R-HSA-6800916) CMTM6 [azurophil granule membrane] (R-HSA-6799141)	0.556	3
UniProt:Q96MX0 CKLF3			0.556	3
UniProt:Q8NDC4 MORN4			0.556	3
UniProt:Q9HB07 MYG1			0.556	3
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:Q9BQE4 SELENOS	1	VIMP [endoplasmic reticulum membrane] (R-HSA-8943099)	0.556	3
UniProt:Q96CM8 ACSF2	1	ACSF2 [mitochondrial matrix] (R-HSA-5696005)	0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3