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APOA1(25-266) [extracellular region]
Stable Identifier
R-HSA-174720
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
apoA-I, apolipoprotein A-I
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Heme signaling (Homo sapiens)
FeHM oxidises LDL,HDL (Homo sapiens)
LDL,HDL [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
oxidized LDL,HDL [extracellular region] (Homo sapiens)
oxidized discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
oxidized spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Release of platelet secretory granule components (Homo sapiens)
Platelet releasate secretory granule proteins [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of APOA1 (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of fat-soluble vitamins (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
CR:atREs binds apoE and HSPG (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
CR:atREs:HSPG:apoE [plasma membrane] (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Cytosolic CMs translocate to extracellular region (Homo sapiens)
nascent CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LDLR transports extracellular CR:atREs to cytosol (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LPL hydrolyses TGs from mature CMs (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
mature CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Homo sapiens)
CR:atREs:HSPG:apoE [plasma membrane] (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Nascent CMs transform into mature CMs (Homo sapiens)
mature CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
nascent CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL:apoC-II:apoC-III:apoE [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
CR:atREs binds apoE and HSPG (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
CR:atREs:HSPG:apoE [plasma membrane] (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Cytosolic CMs translocate to extracellular region (Homo sapiens)
nascent CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LDLR transports extracellular CR:atREs to cytosol (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LPL hydrolyses TGs from mature CMs (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
mature CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Homo sapiens)
CR:atREs:HSPG:apoE [plasma membrane] (Homo sapiens)
CR:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Nascent CMs transform into mature CMs (Homo sapiens)
mature CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
nascent CM:atREs [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL:apoC-II:apoC-III:apoE [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein assembly (Homo sapiens)
Chylomicron assembly (Homo sapiens)
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Homo sapiens)
chylomicron [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
nascent chylomicron [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL:apoC-II:apoC-III:apoE [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Homo sapiens)
nascent chylomicron [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
HDL assembly (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
pre-beta HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
HDL clearance (Homo sapiens)
Disassembly of SR-BI-bound spherical HDL (Homo sapiens)
pre-beta HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
HDLBP binds HDL (Homo sapiens)
HDLBP:HDL [plasma membrane] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
apoA-I binds to CUBN:AMN (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL and SR-BI receptor form a complex at the cell surface (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Plasma lipoprotein remodeling (Homo sapiens)
Chylomicron remodeling (Homo sapiens)
TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Homo sapiens)
TG-depleted chylomicron [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Homo sapiens)
TG-depleted chylomicron [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
chylomicron [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
HDL remodeling (Homo sapiens)
CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex (Homo sapiens)
CETP:spherical HDL:torcetrapib complex [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
CETP-mediated lipid exchange: spherical HDL gains triacylglycerol (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL:triacylglycerol complex [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Discoidal HDL binds membrane-associated free cholesterol (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
discoidal HDL:cholesterol [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Homo sapiens)
LCAT:discoidal HDL complex [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LCAT + spherical HDL <=> LCAT:spherical HDL complex (Homo sapiens)
LCAT:spherical HDL complex [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Homo sapiens)
LCAT:discoidal HDL complex [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
LCAT:spherical HDL complex <=> LCAT + spherical HDL (Homo sapiens)
LCAT:spherical HDL complex [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Spherical HDL binds C and E apolipoproteins (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL:apoC-II:apoC-III:apoE [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Spherical HDL binds membrane-associated free cholesterol and phospholipids (Homo sapiens)
enlarged spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging by Class A Receptors (Homo sapiens)
MSR1 (SCARA1, SR-A) binds ligands (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
MSR1:Ligand [plasma membrane] (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Homo sapiens)
MSR1:Ligand [plasma membrane] (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Scavenging by Class B Receptors (Homo sapiens)
Platelet glycoprotein IV (CD36) binds ligands (Homo sapiens)
Ligands of CD36 [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Platelet glycoprotein IV:Ligand [plasma membrane] (Homo sapiens)
Ligands of CD36 [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Homo sapiens)
Platelet glycoprotein IV:Ligand [plasma membrane] (Homo sapiens)
Ligands of CD36 [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
SCARB1 (SR-BI, CLA-1) binds ligands (Homo sapiens)
Ligands of SCARB1 [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
SCARB1:Ligand [plasma membrane] (Homo sapiens)
Ligands of SCARB1 [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Scavenging of heme from plasma (Homo sapiens)
Haptoglobin-related Protein binds Hemoglobin (Homo sapiens)
HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
Hemoglobin:HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
APOA1(25-266) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02647 APOA1
Gene Names
APOA1
Chain
signal peptide:1-18, chain:19-267, chain:25-267, chain:25-266
Reference Genes
BioGPS Gene:335 APOA1
COSMIC (genes):APOA1 APOA1
CTD Gene:335 APOA1
dbSNP Gene:335 APOA1
ENSEMBL:ENSG00000118137 APOA1
HGNC:600 APOA1
KEGG:hsa:335 APOA1
Monarch:335 APOA1
NCBI Gene:335 APOA1
OMIM:107680 APOA1
UCSC:P02647 APOA1
Reference Transcript
RefSeq:NM_001318018.1 APOA1
RefSeq:NM_001318017.1 APOA1
RefSeq:NM_000039.2 APOA1
RefSeq:NM_001318021.1 APOA1
Other Identifiers
11757663_x_at
11757705_x_at
11757734_x_at
11758012_x_at
11758197_s_at
11758353_s_at
16744723
204450_PM_x_at
204450_x_at
217073_PM_x_at
217073_x_at
335
3392987
3392988
3392989
3392990
3392991
3392992
3392993
3392994
3392995
39106_at
7951865
8077185
A_23_P203191
A_33_P3298539
GE62851
GO:0001540
GO:0001932
GO:0001935
GO:0002719
GO:0005102
GO:0005215
GO:0005319
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005768
GO:0005769
GO:0005788
GO:0005829
GO:0005886
GO:0006629
GO:0006644
GO:0006656
GO:0006695
GO:0006869
GO:0007186
GO:0007229
GO:0008035
GO:0008203
GO:0008211
GO:0008289
GO:0010804
GO:0010875
GO:0010903
GO:0015485
GO:0018158
GO:0018206
GO:0019899
GO:0019915
GO:0030139
GO:0030300
GO:0030301
GO:0030312
GO:0030325
GO:0031012
GO:0031072
GO:0031410
GO:0032489
GO:0032691
GO:0033344
GO:0033700
GO:0034115
GO:0034190
GO:0034191
GO:0034361
GO:0034362
GO:0034364
GO:0034366
GO:0034375
GO:0034380
GO:0034384
GO:0034774
GO:0035025
GO:0042157
GO:0042158
GO:0042627
GO:0042632
GO:0042802
GO:0042803
GO:0043226
GO:0043534
GO:0043691
GO:0045499
GO:0046470
GO:0048018
GO:0048856
GO:0048870
GO:0050728
GO:0050766
GO:0050821
GO:0050919
GO:0051180
GO:0051345
GO:0051496
GO:0055090
GO:0055091
GO:0060228
GO:0060354
GO:0060761
GO:0062023
GO:0065003
GO:0070062
GO:0070328
GO:0070508
GO:0070653
GO:0071402
GO:0071682
GO:0071813
GO:0072562
GO:0090205
GO:0098772
GO:0120020
GO:1900026
GO:1902995
GO:1903561
GO:1905920
HMNXSV003026166
ILMN_1690884
PH_hs_0035488
PH_hs_0036613
TC11002328.hg
X01038_rna1_s_at
g4557320_3p_a_at
Participates
as an output of
Expression of APOA1 (Homo sapiens)
BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Homo sapiens)
as a member of
Platelet releasate secretory granule proteins [extracellular region] (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
as a component of
nascent CM:atREs [extracellular region] (Homo sapiens)
mature CM:atREs [extracellular region] (Homo sapiens)
CR [extracellular region] (Homo sapiens)
spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III [extracellular region] (Homo sapiens)
TG-depleted chylomicron [extracellular region] (Homo sapiens)
enlarged spherical HDL [extracellular region] (Homo sapiens)
chylomicron [extracellular region] (Homo sapiens)
nascent chylomicron [extracellular region] (Homo sapiens)
pre-beta HDL [extracellular region] (Homo sapiens)
HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
oxidized spherical HDL [extracellular region] (Homo sapiens)
oxidized discoidal HDL [extracellular region] (Homo sapiens)
discoidal HDL [extracellular region] (Homo sapiens)
spherical HDL [extracellular region] (Homo sapiens)
as an input of
apoA-I binds to CUBN:AMN (Homo sapiens)
Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Homo sapiens)
This entity regulates
Positively
cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)
(Homo sapiens)
Other forms of this molecule
APOA1 [endoplasmic reticulum lumen]
p-APOA1 [endoplasmic reticulum lumen]
APOA1(25-266) [endocytic vesicle lumen]
Variant apolipoprotein AI [extracellular region]
APOA1(25-266) [plasma membrane]
APOA1(19-266) [extracellular region]
APOA1(25-267) [endoplasmic reticulum lumen]
APOA1(25-267) [early endosome]
APOA1(25-267) [cytosol]
APOA1(25-266) [secretory granule lumen]
Inferred To
apoa1a [extracellular region]
(Danio rerio)
APOA1 [extracellular region]
(Bos taurus)
APOA1 [extracellular region]
(Canis familiaris)
APOA1 [extracellular region]
(Gallus gallus)
APOA1 [extracellular region]
(Sus scrofa)
Apoa1 [extracellular region]
(Mus musculus)
Apoa1 [extracellular region]
(Rattus norvegicus)
Cross References
ENSEMBL
ENSP00000364469
,
ENST00000375323
,
ENST00000236850
,
ENST00000359492
,
ENSG00000118137
,
ENSP00000352471
,
ENSP00000364472
,
ENST00000375320
,
ENSP00000236850
OpenTargets
ENSG00000118137
GeneCards
APOA1
HPA
ENSG00000118137-APOA1
PRO
P02647
Pharos - Targets
P02647
Orphanet
APOA1
GlyGen
P02647
HMDB Protein
HMDBP01620
PDB
2MSC
,
6CCH
,
2MSE
,
2MSD
,
7RSE
,
6W4E
,
6W4F
,
3R2P
,
3K2S
,
1ODP
,
1ODQ
,
2N5E
,
1AV1
,
6PTS
,
1ODR
,
6CCX
,
6CM1
,
7KJR
,
4V6M
,
6CC9
,
8EQS
,
6CLZ
,
1GW3
,
1GW4
,
7RSC
,
6PTW
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02647 APOA1
11
APOA1(25-266) [extracellular region]
(R-HSA-174720)
APOA1 [endoplasmic reticulum lumen]
(R-HSA-8956724)
p-APOA1 [endoplasmic reticulum lumen]
(R-HSA-8957081)
APOA1(25-266) [endocytic vesicle lumen]
(R-HSA-2239460)
Variant apolipoprotein AI [extracellular region]
(R-HSA-976865)
APOA1(25-266) [plasma membrane]
(R-HSA-216742)
APOA1(19-266) [extracellular region]
(R-HSA-264771)
APOA1(25-267) [endoplasmic reticulum lumen]
(R-HSA-174640)
APOA1(25-267) [early endosome]
(R-HSA-2429641)
APOA1(25-267) [cytosol]
(R-HSA-2395781)
APOA1(25-266) [secretory granule lumen]
(R-HSA-350761)
0.972
28
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.747
8
UniProt:Q96DZ9-2 CMTM5
0.718
6
UniProt:Q16659 MAPK6 gene
6
p-3S,T MAPK6 [nucleoplasm]
(R-HSA-5692665)
MAPK6 [nucleoplasm]
(R-HSA-5692686)
p-S189 MAPK6 [nucleoplasm]
(R-HSA-5687015)
p-S189 MAPK6 [cytosol]
(R-HSA-5687019)
MAPK6 [cytosol]
(R-HSA-5686979)
ub-MAPK6 [cytosol]
(R-HSA-5687000)
0.659
3
UniProt:P04180 LCAT
1
LCAT [extracellular region]
(R-HSA-194239)
0.623
2
UniProt:P37840 SNCA
5
SNCA [cytosol]
(R-HSA-5658500)
p-S129-SNCA [cytosol]
(R-HSA-9836432)
Ub-SNCA [cytosol]
(R-HSA-5660754)
SNCA [extracellular region]
(R-HSA-976954)
SNCA A30P [cytosol]
(R-HSA-5658569)
0.623
3
UniProt:O95477 ABCA1
11
ABCA1 [plasma membrane]
(R-HSA-194209)
4xPALM-C-p-2S-ABCA1 [plasma membrane]
(R-HSA-5682069)
4xPALM-C-ABCA1 [endoplasmic reticulum membrane]
(R-HSA-5682085)
4xPALM-C-ABCA1 [plasma membrane]
(R-HSA-5682091)
ABCA1 [endoplasmic reticulum membrane]
(R-HSA-5682105)
ABCA1 Q537R [plasma membrane]
(R-HSA-5682199)
ABCA1 R587W [plasma membrane]
(R-HSA-5682197)
ABCA1 S1446L [plasma membrane]
(R-HSA-5682195)
ABCA1 C1417R [plasma membrane]
(R-HSA-5682190)
ABCA1 N935S [plasma membrane]
(R-HSA-5682200)
ABCA1 W590S [plasma membrane]
(R-HSA-5682201)
0.621
8
UniProt:P00738 HP
7
HP [tertiary granule lumen]
(R-HSA-6800879)
HP [extracellular region]
(R-HSA-6799677)
HP [specific granule lumen]
(R-HSA-6799622)
7xHC-HP(19-160) [extracellular region]
(R-HSA-2168848)
5xHC-HP(162-406) [extracellular region]
(R-HSA-2168875)
7xHC-HP(19-160) [endocytic vesicle lumen]
(R-HSA-2230994)
5xHC-HP(162-406) [endocytic vesicle lumen]
(R-HSA-2230973)
0.558
3
UniProt:P13473-2 P134732
0.556
3
UniProt:Q96DZ9 CKLF5
0.556
3
UniProt:Q9Y371 SHLB1
0.556
3
UniProt:Q96NG5 ZNF558
1
ZNF558 [nucleoplasm]
(R-HSA-1973893)
0.527
2
UniProt:Q9H8H2 DDX31
0.527
2
UniProt:P05091 ALDH2
1
ALDH2 [mitochondrial matrix]
(R-HSA-71718)
0.527
2
UniProt:Q8NHS2 AATC2
0.527
2
UniProt:P60033 CD81
1
CD81 [plasma membrane]
(R-HSA-197933)
0.527
7
UniProt:Q07021 C1QBP
3
C1QBP [cytosol]
(R-HSA-9645690)
C1QBP [mitochondrial matrix]
(R-HSA-9645697)
C1QBP [plasma membrane]
(R-HSA-158123)
0.499
2
UniProt:P23142 FBLN1
1
FBLN1 [extracellular region]
(R-HSA-2161389)
0.488
2
UniProt:P02671 FGA
8
FGA [extracellular region]
(R-HSA-140583)
FGA(20-35) [extracellular region]
(R-HSA-140867)
FGA [plasma membrane]
(R-HSA-140916)
FGA(20-866) [extracellular region]
(R-HSA-140841)
FGA(20-866) [platelet alpha granule lumen]
(R-HSA-140920)
FGA [endoplasmic reticulum lumen]
(R-HSA-8956714)
p-FGA [endoplasmic reticulum lumen]
(R-HSA-8957043)
Variant fibrinogen alpha chain [extracellular region]
(R-HSA-976905)
0.483
2
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