Formation of N-glucuronides

Stable Identifier
R-HSA-174916
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Typical N-centred substrates were chosen as examples for these isozymes.

Literature References
PubMed ID Title Journal Year
14570768 N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases

Kuehl, GE, Murphy, SE

Drug Metab Dispos 2003
12433823 Characterization of nicotine and cotinine N-glucuronidations in human liver microsomes

Nakajima, M, Tanaka, E, Kwon, JT, Yokoi, T

Drug Metab Dispos 2002
15135306 Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4

Kaku, T, Ogura, K, Nishiyama, T, Ohnuma, T, Muro, K, Hiratsuka, A

Biochem Pharmacol 2004
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
glucuronosyltransferase activity of UGT1A3,A4,A9 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Reviewed
Created
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