Reactome | BANF1 [nucleoplasm]

BANF1 [nucleoplasm]

Stable Identifier

R-HSA-175030

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

BAF protein

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
        
        BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Homo sapiens)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)
    - Mitotic Prophase (Homo sapiens)
      - Nuclear Envelope Breakdown (Homo sapiens)
        
        VRK1/VRK2 phosphorylate BANF1 (Homo sapiens)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75531 BANF1

Gene Names

BANF1, BAF, BCRG1

Chain

initiator methionine:1, chain:1-89, chain:2-89

Reference Genes

BioGPS Gene:8815 BANF1

COSMIC (genes):BANF1 BANF1

CTD Gene:8815 BANF1

dbSNP Gene:8815 BANF1

ENSEMBL:ENSG00000175334 BANF1

HGNC:17397 BANF1

KEGG Gene (Homo sapiens):8815 BANF1

Monarch:8815 BANF1

NCBI Gene:8815 BANF1

OMIM:603811 BANF1

UCSC:O75531 BANF1

Reference Transcript

Other Identifiers

0003390242

11716884_a_at

11716885_x_at

11753836_x_at

11754130_a_at

11754131_x_at

11757065_x_at

16727224

210125_s_at

2603240

2603241

2603247

2603249

3335886

3335887

3335888

3335890

3335891

3335892

3335893

38663_at

7941501

8180260

8815

A_23_P47208

GE61222

GE86482

GO:0000278

GO:0000793

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006259

GO:0006810

GO:0007049

GO:0007059

GO:0007084

GO:0008022

GO:0008150

GO:0009615

GO:0015074

GO:0016032

GO:0019899

GO:0030261

GO:0034641

GO:0042802

GO:0042803

GO:0043226

GO:0044403

GO:0045071

GO:0047485

GO:0051169

GO:0051276

GO:0061024

GO:0075713

GO:0097726

ILMN_1749243

ILMN_2179837

PH_hs_0020150

TC11000650.hg

g3002950_3p_s_at

Participant Of

hasComponent

Other forms of this molecule

p-T2,T3,S4-BANF1 [nucleoplasm]

p-T2,T3,S4-BANF1 [cytosol]

BANF1 [cytosol]

Inferred To

Banf1 [nucleoplasm] (Mus musculus)

Banf1 [nucleoplasm] (Rattus norvegicus)

BANF1 [nucleoplasm] (Canis familiaris)

BANF1 [nucleoplasm] (Sus scrofa)

BANF1 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_003851.1, XP_016874003.1, NP_001137457.1, XP_016874004.1

OpenTargets

ENSG00000175334

HPA

ENSG00000175334-BANF1

GeneCards

O75531

Ensembl

ENSP00000310275, ENSG00000175334, ENST00000445560, ENST00000312175, ENSP00000416128, ENSP00000432867, ENST00000527348, ENSP00000433760, ENST00000533166

PRO

O75531

Orphanet

20477

PDB

2BZF, 1QCK, 6GHD, 2EZZ, 2ODG, 2EZX, 1CI4, 6RPR, 2EZY

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P50402 EMD	3	EMD [cytosol] (R-HSA-9613988) EMD [endoplasmic reticulum membrane] (R-HSA-9613998) EMD [nuclear envelope] (R-HSA-201573)	0.908	12
UniProt:O75531 BANF1	4	BANF1 [nucleoplasm] (R-HSA-175030) p-T2,T3,S4-BANF1 [nucleoplasm] (R-HSA-2993896) p-T2,T3,S4-BANF1 [cytosol] (R-HSA-2995375) BANF1 [cytosol] (R-HSA-175371)	0.618	3
UniProt:Q9H503-2 BANF2			0.556	3