Reactome | BANF1 [nucleoplasm]

BANF1 [nucleoplasm]

Stable Identifier

R-HSA-175030

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

BAF protein

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
        
        BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Homo sapiens)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)
    - Mitotic Prophase (Homo sapiens)
      - Nuclear Envelope Breakdown (Homo sapiens)
        
        VRK1/VRK2 phosphorylate BANF1 (Homo sapiens)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)
        
        BANF1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75531 BANF1

Gene Names

BANF1, BAF, BCRG1

Chain

initiator methionine:1, chain:1-89, chain:2-89

Reference Genes

BioGPS Gene:8815 BANF1

COSMIC (genes):BANF1 BANF1

CTD Gene:8815 BANF1

dbSNP Gene:8815 BANF1

ENSEMBL:ENSG00000175334 BANF1

HGNC:17397 BANF1

KEGG Gene (Homo sapiens):8815 BANF1

Monarch:8815 BANF1

NCBI Gene:8815 BANF1

OMIM:603811 BANF1

UCSC:O75531 BANF1

Reference Transcript

Other Identifiers

0003390242

11716884_a_at

11716885_x_at

11753836_x_at

11754130_a_at

11754131_x_at

11757065_x_at

16727224

210125_s_at

2603240

2603241

2603247

2603249

3335886

3335887

3335888

3335890

3335891

3335892

3335893

38663_at

7941501

8180260

8815

A_23_P47208

GE61222

GE86482

GO:0000278

GO:0000793

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006259

GO:0006810

GO:0007049

GO:0007059

GO:0007084

GO:0008022

GO:0008150

GO:0009615

GO:0015074

GO:0016032

GO:0019899

GO:0030261

GO:0034641

GO:0042802

GO:0042803

GO:0043226

GO:0044403

GO:0045071

GO:0047485

GO:0051169

GO:0051276

GO:0061024

GO:0075713

GO:0097726

HMNXSV003039288

ILMN_1749243

ILMN_2179837

PH_hs_0020150

TC11000650.hg

g3002950_3p_s_at

Participates

as a component of

Other forms of this molecule

p-T2,T3,S4-BANF1 [nucleoplasm]

BANF1 [cytosol]

p-T2,T3,S4-BANF1 [cytosol]

Cross References

RefSeq

XP_016874003.1, NP_003851.1, XP_016874004.1, NP_001137457.1

OpenTargets

ENSG00000175334

GeneCards

O75531

HPA

ENSG00000175334-BANF1

Ensembl

ENST00000445560, ENSG00000175334, ENST00000312175, ENSP00000432867, ENSP00000310275, ENST00000533166, ENSP00000416128, ENST00000527348, ENSP00000433760

PRO

O75531

Orphanet

20477

PDB

6US1, 6USB, 6GHD, 1QCK, 6USD, 6URE, 2BZF, 6US0, 6UNT, 6URJ, 2EZY, 6URK, 6URN, 1CI4, 2ODG, 6USI, 6URZ, 2EZX, 6RPR, 6US7, 6URR, 2EZZ, 6URL

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P50402 EMD	4	EMD [cytosol] (R-HSA-9613988) EMD [nuclear envelope] (R-HSA-201573) EMD [endoplasmic reticulum membrane] (R-HSA-9613998) EMD [endosome membrane] (R-HSA-9715092)	0.908	12
UniProt:O75531 BANF1	4	BANF1 [nucleoplasm] (R-HSA-175030) p-T2,T3,S4-BANF1 [nucleoplasm] (R-HSA-2993896) BANF1 [cytosol] (R-HSA-175371) p-T2,T3,S4-BANF1 [cytosol] (R-HSA-2995375)	0.618	3
UniProt:Q9H503-2 BANF2			0.556	3