beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP

Stable Identifier
R-HSA-176521
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Sulfonation of beta-estradiol is catalyzed by SULT1E1 (Falany et al. 1995).

Literature References
PubMed ID Title Journal Year
7779757 Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase

Falany, CN, Krasnykh, V, Falany, JL

J Steroid Biochem Mol Biol 1995
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
steroid sulfotransferase activity of SULT1E1 dimer [cytosol]
Physical Entity
SULT1E1 dimer [cytosol]
Activity
steroid sulfotransferase activity (0050294)
Orthologous Events
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Bos taurus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Caenorhabditis elegans)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Canis familiaris)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Danio rerio)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Drosophila melanogaster)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Gallus gallus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Mus musculus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Rattus norvegicus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Sus scrofa)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Xenopus tropicalis)
Cross References
Rhea
Reviewed
D'Eustachio, P  (2008-05-28)
Created
D'Eustachio, P  (2006-03-09)
Cite Us!