beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP

Stable Identifier
R-HSA-176521
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Sulfonation of beta-estradiol is catalyzed by SULT1E1 (Falany et al. 1995).

Literature References
PubMed ID Title Journal Year
7779757 Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase

Falany, CN, Krasnykh, V, Falany, JL

J Steroid Biochem Mol Biol 1995
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
steroid sulfotransferase activity of SULT1E1 dimer [cytosol]
Physical Entity
SULT1E1 dimer [cytosol]
Activity
steroid sulfotransferase activity (0050294)
Orthologous Events
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Bos taurus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Caenorhabditis elegans)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Canis familiaris)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Danio rerio)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Gallus gallus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Mus musculus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Rattus norvegicus)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Sus scrofa)
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Xenopus tropicalis)
Cross References
Rhea
Reviewed
D'Eustachio, P  (2008-05-28)
Created
D'Eustachio, P  (2006-03-08)