cholesterol + PAPS => cholesterol sulfate + PAP

Stable Identifier
R-HSA-176609
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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The 3-hydroxyl groups of a number of sterols can undergo sulfonation. Cholesterol sulfate is particularly abundant in the body, and may have both regulatory and biosynthetic functions (Strott and Higashi 2003). Its synthesis is catalyzed by the b isoform of SULT2B1 (Fuda et al. 2002; Javitt et al. 2001).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alcohol sulfotransferase activity of SULT2B1-1 dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Reviewed
Created