dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP

Stable Identifier
R-HSA-176631
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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Sulfonation of dehydroepiandrosterone (DHEA) is catalyzed by SULT1E1 (Aksoy et al. 1994), SULT2A1 (Radominska et al. 1990) and the a and b isoforms of SULT2B1 (Meloche and Falany 2001).

Literature References
PubMed ID Title Journal Year
2268288 Human liver steroid sulphotransferase sulphates bile acids

Radominska, A, Comer, KA, Zimniak, P, Falany, JL, Iscan, M, Falany, CN

Biochem J 1990
8185618 Human liver estrogen sulfotransferase: identification by cDNA cloning and expression

Aksoy, IA, Weinshilboum, RM, Wood, TC

Biochem Biophys Res Commun 1994
11457664 Expression and characterization of the human 3 beta-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b)

Meloche, CA, Falany, CN

J Steroid Biochem Mol Biol 2001
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
steroid sulfotransferase activity of SULTs active on DHEA [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Reviewed
Created