estrone + PAPS => estrone 3-sulfate + PAP

Stable Identifier
R-HSA-176664
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Sulfonation of estrone is catalyzed by SULT1E1 (Aksoy et al. 1994; Falany et al. 1995), and also by SULT2A1 (Comer et al. 1993), although the efficiency of SULT2A1 catalysis is unknown.

Literature References
PubMed ID Title Journal Year
8185618 Human liver estrogen sulfotransferase: identification by cDNA cloning and expression

Aksoy, IA, Weinshilboum, RM, Wood, TC

Biochem Biophys Res Commun 1994
7678732 Cloning and expression of human liver dehydroepiandrosterone sulphotransferase

Comer, KA, Falany, JL, Falany, CN

Biochem J 1993
7779757 Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase

Falany, CN, Krasnykh, V, Falany, JL

J Steroid Biochem Mol Biol 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
estrone sulfotransferase activity of SULT1E1,2A1 [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Reviewed
Created