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p-2S-SMAD2,3 [nucleoplasm]
Stable Identifier
R-HSA-177105
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Phospho-R-SMAD
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of axial mesoderm (Homo sapiens)
Expression of FOXA2 in the anterior primitive streak (Homo sapiens)
TEAD2,TEAD4:YAP1:FOXH1:p-SMAD2,3:TBXT:FOXA2 gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene (Homo sapiens)
TEAD2,TEAD4:YAP1:FOXH1:p-SMAD2,3:TBXT:FOXA2 gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
Germ layer formation at gastrulation (Homo sapiens)
Expression of Goosecoid (GSC) in the primitive streak (Homo sapiens)
p-2S-SMAD2,3:SMAD4:TRIM33:CTNNB1:FOXH1:SMAD3:EOMES:TBPL2:GSC gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
Expression of MIXL1 in the primitive streak (Homo sapiens)
p-2S-SMAD2,3:TRIM33:p-2S-SMAD2,3:SMAD4:CTNNB1:FOXH1:EOMES:TBPL2:MIXL1 gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene (Homo sapiens)
p-2S-SMAD2,3:SMAD4:TRIM33:CTNNB1:FOXH1:SMAD3:EOMES:TBPL2:GSC gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33, p-2S-SMAD2,3:SMAD4, CTNNB1, EOMES, and TBPL2 bind FOXH1:MIXL1 gene (Homo sapiens)
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33:p-2S-SMAD2,3:SMAD4:CTNNB1:FOXH1:EOMES:TBPL2:MIXL1 gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
TRIM33 monoubiquitinates SMAD4 (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
TRIM33 monoubiquitinates SMAD4 (Homo sapiens)
p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)
Participants
members
p-S465,S467-SMAD2 [nucleoplasm]
(Homo sapiens)
p-S423,S425-SMAD3 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
p-2S-SMAD2,3:TRIM33 [nucleoplasm] (Homo sapiens)
TEAD2,TEAD4:YAP1:FOXH1:p-SMAD2,3:TBXT:FOXA2 gene [nucleoplasm] (Homo sapiens)
as an input of
TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene (Homo sapiens)
as an output of
TRIM33 monoubiquitinates SMAD4 (Homo sapiens)
Inferred To
p-2S-SMAD2,3 [nucleoplasm]
(Bos taurus)
p-2S-SMAD2,3 [nucleoplasm]
(Canis familiaris)
p-2S-SMAD2,3 [nucleoplasm]
(Danio rerio)
p-2S-SMAD2,3 [nucleoplasm]
(Gallus gallus)
p-2S-SMAD2,3 [nucleoplasm]
(Rattus norvegicus)
p-2S-SMAD2,3 [nucleoplasm]
(Sus scrofa)
phospho-Smad2,3 [nucleoplasm]
(Mus musculus)
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