Multiubiquitination of Nek2A

Stable Identifier
R-HSA-179417
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Nek2A is ubiquitinated by the APC/C-Cdc20 ubiquitin ligase.

Literature References
PubMed ID Title Journal Year
11742988 APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

Hames, RS, Wattam, SL, Yamano, H, Bacchieri, R, Fry, AM

EMBO J 2001
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of Nek2A:MCC:APC/C complex [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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