EGFR

Stable Identifier
R-HSA-179837
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Epidermal Growth Factor Receptor
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
EGFR, ERBB, ERBB1, HER1
Chain
signal peptide:1-24, chain:25-1210
Other Identifiers
0000840253
0002940025
0005900148
0006350504
11725102_at
11725103_s_at
11725104_a_at
11733760_a_at
11738815_at
11742247_a_at
11751983_a_at
1200
1537_at
1565483_at
1565484_x_at
17046135
18530
1956
1DNQ
1DNR
1IVO
1M14
1M17
1MOX
1NQL
1XKK
1YY9
1Z9I
201983_s_at
201984_s_at
210984_x_at
211550_at
211607_x_at
224999_at
2EB2
2EB3
2EXP
2EXQ
2GS2
2GS6
2GS7
2ITN
2ITO
2ITP
2ITQ
2ITT
2ITU
2ITV
2ITW
2ITX
2ITY
2ITZ
2J5E
2J5F
2J6M
2JIT
2JIU
2JIV
2KS1
2M0B
2M20
2N5S
2RF9
2RFD
2RFE
2RGP
3002641
3002642
3002729
3002731
3002733
3002738
3002741
3002743
3002747
3002749
3002750
3002751
3002753
3002757
3002760
3002761
3002763
3002767
3002769
3002770
3002771
3002775
3002776
3002778
3002779
3002786
3002798
3002800
3002801
3002802
3002806
3002807
3002808
3002811
3002812
3002813
3002814
3002815
3002816
3002817
3002818
3002819
3002820
35
37327_at
3B2U
3B2V
3BEL
3BUO
3C09
3G5V
3G5Y
3GT8
3IKA
3LZB
3NJP
3OB2
3OP0
3P0Y
3PFV
3POZ
3QWQ
3UG1
3UG2
3VJN
3VJO
3VRP
3VRR
3W2O
3W2P
3W2Q
3W2R
3W2S
3W32
3W33
48285_at
4G5J
4G5P
4HJO
4I1Z
4I20
4I21
4I22
4I23
4I24
4JQ7
4JQ8
4JR3
4JRV
4KRL
4KRM
4KRO
4KRP
4LI5
4LL0
4LQM
4LRM
4R3P
4R3R
4R5S
4RIW
4RIX
4RIY
4RJ4
4RJ5
4RJ6
4RJ7
4RJ8
4TKS
4UIP
4UV7
4WD5
4WKQ
4WRG
4ZAU
4ZJV
4ZSE
5C8K
5C8M
5C8N
5CAL
5CAN
5CAO
5CAP
5CAQ
5CAS
5CAU
5CAV
5CNN
5CNO
5CZH
5CZI
5D41
5EDP
5EDQ
5EDR
5EM5
5EM6
5EM7
5EM8
5FED
5FEE
5FEQ
5GNK
5HCX
5HCY
5HCZ
5HG5
5HG7
5HG8
5HG9
5HIB
5HIC
5J9Y
5J9Z
5JEB
5LV6
5SX4
5SX5
5U8L
5UG8
5UG9
5UGA
5UGB
5UGC
65700_at
68186
73534
8132860
A_14_P106592
A_23_P215790
A_33_P3351944
A_33_P3351955
AAA52370
AAA63171
AAB53063
AAC50796
AAC50797
AAC50798
AAC50799
AAC50800
AAC50801
AAC50802
AAC50804
AAG35786
AAG35787
AAG35788
AAG35789
AAG35790
AAG43240
AAG43243
AAK01080
AAS83109
AAT97979
AF125253
AF125538
AF125539
AF277897
AF288738
AY588246
AY698024
CAA25240
CAA25282
CAA29668
CAB000035
CAB068186
CAB073534
CCDS47587
CCDS5514
CCDS5515
CCDS5516
EGFR
EGFR-201
EGFR-202
EGFR-203
EGFR-204
ENSG00000146648
ENSP00000275493
ENSP00000342376
ENSP00000345973
ENSP00000413843
ENST00000275493
ENST00000342916
ENST00000344576
ENST00000420316
EntrezGene:1956
g12002211_3p_at
g1628549_3p_s_at
g4885198_3p_a_at
GE59632
GO:0000003
GO:0000139
GO:0000165
GO:0000166
GO:0000186
GO:0000278
GO:0000902
GO:0001503
GO:0001889
GO:0001892
GO:0001934
GO:0001942
GO:0001948
GO:0003013
GO:0003674
GO:0003677
GO:0003682
GO:0003690
GO:0004672
GO:0004709
GO:0004713
GO:0004714
GO:0004716
GO:0004871
GO:0004888
GO:0005006
GO:0005088
GO:0005102
GO:0005178
GO:0005515
GO:0005516
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005737
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0005925
GO:0006259
GO:0006357
GO:0006412
GO:0006464
GO:0006468
GO:0006605
GO:0006629
GO:0006810
GO:0006913
GO:0006950
GO:0006970
GO:0006979
GO:0007009
GO:0007049
GO:0007155
GO:0007165
GO:0007166
GO:0007169
GO:0007173
GO:0007202
GO:0007267
GO:0007275
GO:0007435
GO:0007494
GO:0007611
GO:0007623
GO:0008092
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0008544
GO:0009056
GO:0009058
GO:0009790
GO:0009986
GO:0010008
GO:0010960
GO:0014066
GO:0014070
GO:0016020
GO:0016021
GO:0016101
GO:0016301
GO:0016310
GO:0016323
GO:0016324
GO:0016337
GO:0016740
GO:0018108
GO:0019899
GO:0019901
GO:0019903
GO:0021795
GO:0030122
GO:0030139
GO:0030154
GO:0030234
GO:0030235
GO:0030307
GO:0030324
GO:0030335
GO:0030665
GO:0031410
GO:0031625
GO:0031659
GO:0031901
GO:0031965
GO:0032355
GO:0032930
GO:0033590
GO:0033594
GO:0033993
GO:0034614
GO:0034641
GO:0035413
GO:0035556
GO:0035690
GO:0038083
GO:0038128
GO:0040007
GO:0040011
GO:0042059
GO:0042060
GO:0042127
GO:0042177
GO:0042327
GO:0042592
GO:0042698
GO:0042743
GO:0042802
GO:0043006
GO:0043066
GO:0043167
GO:0043226
GO:0043234
GO:0043235
GO:0043406
GO:0043547
GO:0043586
GO:0045121
GO:0045202
GO:0045296
GO:0045429
GO:0045739
GO:0045740
GO:0045780
GO:0045893
GO:0045907
GO:0045930
GO:0045944
GO:0046328
GO:0046777
GO:0046854
GO:0046934
GO:0046982
GO:0048015
GO:0048143
GO:0048146
GO:0048408
GO:0048471
GO:0048546
GO:0048661
GO:0048812
GO:0048856
GO:0048870
GO:0050679
GO:0050729
GO:0050730
GO:0050877
GO:0050999
GO:0051015
GO:0051205
GO:0051592
GO:0051897
GO:0051968
GO:0060571
GO:0061024
GO:0061029
GO:0070141
GO:0070372
GO:0070374
GO:0070435
GO:0071230
GO:0071260
GO:0071276
GO:0071363
GO:0071364
GO:0071392
GO:0071549
GO:0097421
GO:0097489
GO:0097755
GO:1900020
GO:1901185
GO:1901224
GO:1902722
GO:1903078
GO:1903800
GO:1905208
GO:2000145
HGNC:3236
HPA001200
HPA018530
Hs.279898.0.S1_3p_at
Hs.77432.0.S1_3p_a_at
Hs2.367845.1.S1_3p_at
Hs2.367845.1.S1_3p_x_at
ILMN_1728858
ILMN_1755535
ILMN_1798975
IPR000494
IPR000719
IPR001245
IPR006211
IPR006212
IPR008266
IPR009030
IPR011009
IPR016245
IPR017441
IPR020635
IPR032675
IPR032778
LRG_304
LRG_304t1
M11234
M38425
MIM:131550
MIM:211980
MIM:616069
NM_005228
NM_201282
NM_201283
NM_201284
NP_001333827
NP_001333829
NP_005219
NP_958439
NP_958440
NP_958441
PF00757
PF01030
PF07714
PF14843
PH_hs_0004462
PH_hs_0014421
PR00109
Q504U8
SM00219
SM00261
TC07000328.hg
TC07002321.hg
U48722
U48723
U48724
U48725
U48726
U48727
U48728
U48729
U95089
uc003tqh.4
uc003tqi.3
uc003tqj.4
uc003tqk.4
UPI000002A8C9
UPI000002A8CA
UPI000002A8CB
UPI000003E750
X00588
X00588_at
X00663
X06370
Participant Of
Other forms of this molecule
Inferred To
Cross References
ZINC - World Drugs
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
UCSC human
ZINC - Metabolites
GeneCards
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.978 P62993 GRB2_HUMAN 47
0.972 P00533 EGFR_HUMAN 23
0.962 P22681 CBL_HUMAN 25
0.961 P29353 SHC1_HUMAN 33
0.953 P04626 ERBB2_HUMAN 21
0.903 P01133 EGF_HUMAN 16
0.893 P40763 STAT3_HUMAN 14
0.882 P21860 ERBB3_HUMAN 12
0.85 P19174 PLCG1_HUMAN 6
0.839 P08238 HS90B_HUMAN 8
0.822 P18031 PTN1_HUMAN 7
0.818 P12931 SRC_HUMAN 7
0.809 P08107 HSP71_HUMAN 6
0.809 P27348 1433T_HUMAN 6
0.802 P20417 PTN1_RAT 11
0.779 P31947 1433S_HUMAN 8
0.779 P27986 P85A_HUMAN 6
0.766 P15941 MUC1_HUMAN 5
0.763 P07948 LYN_HUMAN 6
0.756 P62158 CALM_HUMAN 4
0.755 O00750 P3C2B_HUMAN 9
0.753 Q9UBN7 HDAC6_HUMAN 11
0.744 P16885 PLCG2_HUMAN 5
0.723 P08581 MET_HUMAN 7
0.721 P04406 G3P_HUMAN 6
0.721 P10599 THIO_HUMAN 4
0.716 P11142 HSP7C_HUMAN 5
0.706 P42224 STAT1_HUMAN 6
0.704 P16333 NCK1_HUMAN 4
0.704 Q92569 P55G_HUMAN 6
0.701 P63104 1433Z_HUMAN 5
0.701 P04083 ANXA1_HUMAN 4
0.692 P46109 CRKL_HUMAN 4
0.688 Q9UJM3 ERRFI_HUMAN 8
0.678 P12830 CADH1_HUMAN 3
0.669 P04792 HSPB1_HUMAN 3
0.669 P35221 CTNA1_HUMAN 4
0.668 Q05209 PTN12_HUMAN 3
0.667 P07900 HS90A_HUMAN 5
0.659 Q71U36 TBA1A_HUMAN 3
0.659 O60716 CTND1_HUMAN 4
0.659 Q03135 CAV1_HUMAN 5
0.659 P38646 GRP75_HUMAN 4
0.658 Q92625 ANS1A_HUMAN 5
0.658 Q92870 APBB2_HUMAN 6
0.658 Q9NSE2 CISH_HUMAN 3
0.646 Q13322 GRB10_HUMAN 3
0.643 P08195 4F2_HUMAN 5
0.635 Q9UNE7 CHIP_HUMAN 3
0.628 Q14457 BECN1_HUMAN 7
0.626 P46940 IQGA1_HUMAN 4
0.623 Q96B97 SH3K1_HUMAN 3
0.623 Q16543 CDC37_HUMAN 9
0.619 Q99418 CYH2_HUMAN 5
0.609 Q06124 PTN11_HUMAN 4
0.602 O14965 AURKA_HUMAN 4
0.599 Q9UJ41 RABX5_HUMAN 4
0.599 P07992 ERCC1_HUMAN 21
0.599 Q86VI4 LAP4B_HUMAN 10
0.592 Q9NRF2 SH2B1_HUMAN 2
0.592 P00519 ABL1_HUMAN 2
0.592 P51451 BLK_HUMAN 2
0.592 P46108 CRK_HUMAN 3
0.592 P43403 ZAP70_HUMAN 2
0.592 O00459 P85B_HUMAN 3
0.592 Q13387 JIP2_HUMAN 4
0.592 P01135 TGFA_HUMAN 2
0.592 P42684 ABL2_HUMAN 8
0.592 Q13239 SLAP1_HUMAN 2
0.581 Q14318 FKBP8_HUMAN 3
0.581 P29353-7 SHC1 4
0.581 Q68CZ2 TENS3_HUMAN 4
0.581 P16234 PGFRA_HUMAN 3
0.576 Q01973 ROR1_HUMAN 8
0.576 P17936 IBP3_HUMAN 3
0.573 P08631 HCK_HUMAN 2
0.573 Q99962 SH3G2_HUMAN 3
0.573 O75368 SH3L1_HUMAN 2
0.573 P41240 CSK_HUMAN 2
0.573 Q8WUM4 PDC6I_HUMAN 3
0.573 O60603 TLR2_HUMAN 2
0.564 Q92622 RUBIC_HUMAN 3
0.564 P07947 YES_HUMAN 3
0.556 O75674 TM1L1_HUMAN 6
0.556 P97313 PRKDC_MOUSE 4
0.556 Q8IZV2 CKLF8_HUMAN 3
0.553 P34932 HSP74_HUMAN 2
0.553 P23528 COF1_HUMAN 2
0.547 Q09666 AHNK_HUMAN 3
0.547 P06493 CDK1_HUMAN 2
0.547 Q9UQB8 BAIP2_HUMAN 2
0.547 Q05397 FAK1_HUMAN 3
0.547 Q96CW1 AP2M1_HUMAN 4
0.547 P51636 CAV2_HUMAN 2
0.547 Q13480 GAB1_HUMAN 3
0.544 Q38SD2 LRRK1_HUMAN 2
0.544 P07948-1 LYN 2
0.527 Q00325 MPCP_HUMAN 3
0.527 O95782 AP2A1_HUMAN 4
0.527 P11021 GRP78_HUMAN 5
0.527 O60884 DNJA2_HUMAN 2
0.527 P68366 TBA4A_HUMAN 2
0.527 Q9UQC2 GAB2_HUMAN 2
0.527 P31943 HNRH1_HUMAN 2
0.527 Q9H0D6 XRN2_HUMAN 5
0.527 P16615 AT2A2_HUMAN 2
0.524 P30530 UFO_HUMAN 4
0.524 P62161 CALM_RAT 6
0.524 P03372-4 ESR1 4
0.524 P13866 SC5A1_HUMAN 3
0.508 P04150 GCR_HUMAN 2
0.508 O75791 GRAP2_HUMAN 2
0.508 Q6S5L8 SHC4_HUMAN 2
0.508 Q12933 TRAF2_HUMAN 3
0.508 P46108-1 CRK 3
0.508 Q9P0L0 VAPA_HUMAN 2
0.508 Q12929 EPS8_HUMAN 2
0.508 Q8WUI4 HDAC7_HUMAN 2
0.508 P49069 CAMLG_HUMAN 2
0.508 Q14247 SRC8_HUMAN 3
0.508 P60520 GBRL2_HUMAN 2
0.508 P31948 STIP1_HUMAN 2
0.508 Q9Y2R2 PTN22_HUMAN 2
0.508 Q9BRG2 SH23A_HUMAN 2
0.508 Q02952 AKA12_HUMAN 2
0.508 P17252 KPCA_HUMAN 2
0.508 Q13094 LCP2_HUMAN 2
0.508 Q9Y2H9 MAST1_HUMAN 2
0.508 O43561 LAT_HUMAN 2
0.508 P09936 UCHL1_HUMAN 2
0.508 P42229 STA5A_HUMAN 3
0.508 P09769 FGR_HUMAN 2
0.499 Q96A65 EXOC4_HUMAN 2
0.499 P22682 CBL_MOUSE 2
0.499 Q80U62 RUBIC_MOUSE 2
0.482 Q12852 M3K12_HUMAN 2
0.463 Q9UPT5 EXOC7_HUMAN 2
0.463 P25098 ARBK1_HUMAN 3
0.463 Q13671 RIN1_HUMAN 3
0.463 P0A0I7 AGRA_STAAU 2
0.463 O75886 STAM2_HUMAN 2
0.462 Q8TF42 UBS3B_HUMAN 5