Association of Vpu with CD4

Stable Identifier
R-HSA-180606
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Vpu is expressed in the ER and associates with a membrane-proximal region in the cytoplasmic tail of CD4.
Literature References
PubMed ID Title Journal Year
9660940 A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

Margottin, F, Richard, V, Benarous, R, Durand, H, Selig, L, Strebel, K, Bour, SP, Thomas, D, Benichou, S

Mol Cell 1998
Participants
Participates
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Reviewed
Created
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