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SACM1L [Golgi membrane]
Stable Identifier
R-HSA-1806242
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
KIAA0851
Locations in the PathwayBrowser for interactor UniProt:P31513 FMO3
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the Golgi membrane (Homo sapiens)
PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Homo sapiens)
SACM1L [Golgi membrane] (Homo sapiens)
PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Homo sapiens)
SACM1L [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NTJ5 SACM1L
Gene Names
SACM1L, KIAA0851, SAC1
Chain
chain:1-587
Reference Genes
BioGPS Gene:22908 SACM1L
COSMIC (genes):SACM1L SACM1L
CTD Gene:22908 SACM1L
dbSNP Gene:22908 SACM1L
ENSEMBL:ENSG00000211456 SACM1L
HGNC:17059 SACM1L
KEGG:hsa:22908 SACM1L
Monarch:22908 SACM1L
NCBI Gene:22908 SACM1L
OMIM:606569 SACM1L
UCSC:Q9NTJ5 SACM1L
Reference Transcript
RefSeq:NM_001319073.1 SACM1L
RefSeq:NM_001319072.1 SACM1L
RefSeq:XM_011533500.2 SACM1L
RefSeq:NM_014016.4 SACM1L
Other Identifiers
11741011_a_at
11747673_a_at
11755387_a_at
16940110
202797_PM_at
202797_at
22908
2445199
2620686
2620687
2620689
2620690
2620691
2620692
2620693
2620694
2620695
2620696
2620697
2620698
2620699
2620700
2620701
2620702
2620703
2620705
2620706
2620707
2620708
2620709
2620710
2620711
2620712
2620713
2620714
2620715
2620716
2620717
2620718
2620719
2620720
2620721
2620722
2620724
2620725
3342591
36511_at
48212_at
8079346
8079368
83475_r_at
A_14_P100053
A_23_P212383
GE53539
GO:0000139
GO:0003824
GO:0004438
GO:0005515
GO:0005783
GO:0005789
GO:0005794
GO:0006629
GO:0006661
GO:0016020
GO:0016787
GO:0016791
GO:0034596
GO:0043226
GO:0043812
GO:0046856
GO:0140268
HMNXSV003021609
HMNXSV003052002
ILMN_1765019
PH_hs_0000594
TC03000250.hg
g7662337_3p_at
Other forms of this molecule
SACM1L [endoplasmic reticulum membrane]
Inferred To
SAC1 [Golgi membrane]
(Saccharomyces cerevisiae)
sacm-1l [Golgi membrane]
(Caenorhabditis elegans)
SACM1L [Golgi membrane]
(Bos taurus)
SACM1L [Golgi membrane]
(Canis familiaris)
SACM1L [Golgi membrane]
(Gallus gallus)
SACM1L [Golgi membrane]
(Plasmodium falciparum)
SACM1L [Golgi membrane]
(Schizosaccharomyces pombe)
SACM1L [Golgi membrane]
(Sus scrofa)
sac1 [Golgi membrane]
(Dictyostelium discoideum)
sacm1lb [Golgi membrane]
(Danio rerio)
Sac1 [Golgi membrane]
(Drosophila melanogaster)
Sacm1l [Golgi membrane]
(Mus musculus)
Sacm1l [Golgi membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011531802.1
,
NP_001306001.1
,
NP_001306002.1
,
NP_054735.3
OpenTargets
ENSG00000211456
ENSEMBL
ENSP00000373713
,
ENST00000438671
,
ENSP00000411966
,
ENST00000389061
IntEnz
3.1.3.64
HPA
ENSG00000211456-SACM1L
PRO
Q9NTJ5
Pharos - Targets
Q9NTJ5
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y678 COPG1
4
COPG1 [endoplasmic reticulum membrane]
(R-HSA-6810960)
COPG1 [Golgi membrane]
(R-HSA-6808747)
COPG1 [transport vesicle]
(R-HSA-6808749)
COPG1 [cytosol]
(R-HSA-199987)
0.677
6
UniProt:O14579 COPE
4
COPE [endoplasmic reticulum membrane]
(R-HSA-6810959)
COPE [Golgi membrane]
(R-HSA-6808743)
COPE [transport vesicle]
(R-HSA-6808745)
COPE [cytosol]
(R-HSA-199969)
0.643
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.601
6
UniProt:Q14973 SLC10A1
1
SLC10A1 [plasma membrane]
(R-HSA-194116)
0.556
3
UniProt:Q9Y394 DHRS7
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:Q5T4F4 ZFY27
0.556
3
UniProt:Q9NRX6 KISHB
0.556
3
UniProt:Q49AM1 MTEF2
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
UniProt:O15552 FFAR2
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
UniProt:P30825 SLC7A1
1
SLC7A1 [plasma membrane]
(R-HSA-375771)
0.556
3
UniProt:P31513 FMO3
6
FMO3 M66I [endoplasmic reticulum membrane]
(R-HSA-5603010)
FMO3 E32K [endoplasmic reticulum membrane]
(R-HSA-5602848)
FMO3 R492W [endoplasmic reticulum membrane]
(R-HSA-5602849)
FMO3 N61S [endoplasmic reticulum membrane]
(R-HSA-5602964)
FMO3 P153L [endoplasmic reticulum membrane]
(R-HSA-5602837)
FMO3 [endoplasmic reticulum membrane]
(R-HSA-54929)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q9NY72 SCN3B
1
SCN3B [plasma membrane]
(R-HSA-197921)
0.556
3
UniProt:Q9BS91 S35A5
0.556
3
UniProt:Q5SR56 MF14B
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:Q2M2E3 ODFP4
0.556
3
UniProt:Q6ZMZ0 RNF19B
1
RNF19B [cytosol]
(R-HSA-975969)
0.556
3
UniProt:Q9NQQ7-3 Q9NQQ73
0.556
3
UniProt:Q9Y320 TMX2
0.556
3
UniProt:Q8TDV0 GP151
0.556
3
UniProt:Q8TDT2 GP152
0.556
3
UniProt:Q9GZY8-5 MFF
0.556
3
IntAct:EBI-23194662 CCSB ORF ID
0.556
3
UniProt:Q7Z5P4 HSD17B13
1
HSD17B13 [cytosol]
(R-HSA-8862029)
0.556
3
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:O95197-3 RTN3
0.556
3
UniProt:O00590 ACKR2
1
ACKR2 [plasma membrane]
(R-HSA-443955)
0.556
3
UniProt:P58658 EVA1C
0.527
3
UniProt:Q92633 LPAR1
1
LPAR1 [plasma membrane]
(R-HSA-419354)
0.527
2
UniProt:Q9H244 P2RY12
1
P2RY12 [plasma membrane]
(R-HSA-391959)
0.527
2
UniProt:P53621 COPA
4
COPA [endoplasmic reticulum membrane]
(R-HSA-6810953)
COPA [Golgi membrane]
(R-HSA-6808731)
COPA [transport vesicle]
(R-HSA-6808732)
COPA [cytosol]
(R-HSA-199978)
0.527
2
UniProt:Q8IVM8 S22A9
0.527
2
UniProt:Q92544 TM9S4
0.527
2
UniProt:P0DTD1-PRO_0000449629 REP
0.488
2
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
5
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