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PIKFYVE [early endosome membrane]
Stable Identifier
R-HSA-1806280
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome membrane
Synonyms
1-phosphatidylinositol-3-phosphate 5-kinase, FYV1_HUMAN, PIP5K3, KIAA0981
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the early endosome membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Homo sapiens)
PIKFYVE:VAC14:FIG4 [early endosome membrane] (Homo sapiens)
PIKFYVE [early endosome membrane] (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)
PIKFYVE [early endosome membrane] (Homo sapiens)
PIKFYVE:VAC14:FIG4 [early endosome membrane] (Homo sapiens)
PIKFYVE [early endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y2I7 PIKFYVE
Gene Names
PIKFYVE, KIAA0981, PIP5K3
Chain
initiator methionine:, chain:2-2098
Reference Genes
BioGPS Gene:200576 PIKFYVE
COSMIC (genes):PIKFYVE PIKFYVE
CTD Gene:200576 PIKFYVE
dbSNP Gene:200576 PIKFYVE
ENSEMBL:ENSG00000115020 PIKFYVE
HGNC:23785 PIKFYVE
KEGG:hsa:200576 PIKFYVE
Monarch:200576 PIKFYVE
NCBI Gene:200576 PIKFYVE
OMIM:609414 PIKFYVE
UCSC:Q9Y2I7 PIKFYVE
Reference Transcript
RefSeq:NM_015040.3 PIKFYVE
RefSeq:NM_152671.3 PIKFYVE
RefSeq:NM_001178000.1 PIKFYVE
Other Identifiers
11724361_s_at
11724362_at
11738109_a_at
11738110_at
11752532_a_at
1553917_PM_at
1553917_at
1557719_PM_at
1557719_at
16890126
200576
213111_PM_at
213111_at
2525273
2525275
2525277
2525278
2525279
2525280
2525284
2525285
2525286
2525287
2525290
2525292
2525295
2525296
2525297
2525300
2525301
2525302
2525307
2525308
2525309
2525310
2525312
2525314
2525316
2525317
2525318
2525319
2525320
2525321
2525323
2525324
2525325
2525326
2525327
2525328
2525329
2525330
2525332
2525333
2525334
2525336
2525338
2525339
2525340
2525341
2525343
2525345
2525347
2525348
2525349
32085_at
42737_at
42738_g_at
8047865
A_14_P136684
A_23_P400984
A_24_P943957
A_33_P3348973
GE484731
GE53635
GO:0000139
GO:0000285
GO:0002376
GO:0003824
GO:0004674
GO:0005515
GO:0005524
GO:0005768
GO:0005829
GO:0005911
GO:0006612
GO:0006629
GO:0006661
GO:0008270
GO:0010008
GO:0012506
GO:0016020
GO:0016192
GO:0016301
GO:0016308
GO:0016740
GO:0016787
GO:0019065
GO:0019886
GO:0030593
GO:0030670
GO:0031410
GO:0031901
GO:0031902
GO:0032288
GO:0032438
GO:0034504
GO:0035556
GO:0036092
GO:0036289
GO:0042147
GO:0043226
GO:0043813
GO:0045121
GO:0046488
GO:0046872
GO:0048471
GO:0048870
GO:0052742
GO:0052810
GO:0061024
GO:0090382
GO:0090385
GO:0106310
GO:0140096
GO:1903100
GO:1903426
GO:1904562
GO:2000785
HMNXSV003022981
HMNXSV003036623
HMNXSV003048065
Hs.158135.0.S1_3p_at
Hs2.375109.1.S1_3p_at
Hs2.406929.1.S1_3p_at
ILMN_1671108
ILMN_1742197
ILMN_1743535
PH_hs_0031907
TC02001235.hg
Participates
as a component of
PIKFYVE:VAC14:FIG4 [early endosome membrane] (Homo sapiens)
Other forms of this molecule
PIKFYVE [late endosome membrane]
PIKFYVE [Golgi membrane]
Inferred To
Pikfyve [early endosome membrane]
(Rattus norvegicus)
PIKFYVE [early endosome membrane]
(Bos taurus)
PIKFYVE [early endosome membrane]
(Canis familiaris)
PIKFYVE [early endosome membrane]
(Gallus gallus)
PIKFYVE [early endosome membrane]
(Mus musculus)
PIKFYVE [early endosome membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001171471.1
,
NP_055855.2
,
NP_689884.1
Guide to Pharmacology - Targets
2857
ENSEMBL
ENSP00000376038
,
ENST00000407449
,
ENSP00000264380
,
ENST00000308862
,
ENSP00000384356
,
ENST00000264380
,
ENST00000392202
,
ENSP00000308715
OpenTargets
ENSG00000115020
IntEnz
2.7.11.1
HPA
ENSG00000115020-PIKFYVE
PRO
Q9Y2I7
Pharos - Targets
Q9Y2I7
GlyGen
Q9Y2I7
Orphanet
PIKFYVE
HMDB Protein
HMDBP01276
PDB
7K2V
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