Conversion of Ran-GDP to Ran-GTP

Stable Identifier
R-HSA-180687
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Free, nuclear RanGTP is required for export processes out of the nucleus. RCC1 catalyses the conversion of Ran-GDP to Ran-GTP in the nucleus.

Literature References
PubMed ID Title Journal Year
1944575 Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

Bischoff, FR, Ponstingl, H

Nature 1991
7878053 Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport

Bischoff, FR, Krebber, H, Kempf, T, Hermes, I, Ponstingl, H

Proc Natl Acad Sci U S A 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
Ran guanyl-nucleotide exchange factor activity of RCC1 [nucleoplasm]
Physical Entity
Activity
Authored
Reviewed
Created